Nevus Lipomatosus Cutaneous Superficialis: A Case Report and Literature Review
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Keywords

Connective Tissue
Hamartoma
Skin Neoplasms

How to Cite

Kiat Yeak, R. D. ., Yap, Y. Y., & M. Nasir, N. . (2020). Nevus Lipomatosus Cutaneous Superficialis: A Case Report and Literature Review. Iranian Red Crescent Medical Journal, 22(6). Retrieved from https://ircmj.com/index.php/IRCMJ/article/view/794

Abstract

Introduction: Nevus lipomatosus cutaneous superficialis (NLCS) is uncommon and can be encountered in various medical special- ties. In this study, we report a rare case of solitary pedunculated nevus lipomatosus cutaneous superficialis in a middle-aged female patient and highlight its clinical and histopathological features.

Case Presentation: A 43-year-old Malaysian female patient presented to our center with a 2-cm long and 1-cm wide solitary, flesh- colored nodule over the anterolateral aspect of her thigh. Excisional biopsy was performed, and the histopathology report showed NLCS. There are three types of NLCS, namely the solitary, multiple, and generalized forms. The etiology of NLCS is usually idiopathic, with no gender or familial preponderance. NLCS is usually misdiagnosed and should be differentiated from nevus sebaceous, con- nective tissue nevus, neurofibroma, lymphangioma, hemangioma, and focal dermal hypoplasia (also known as Goltz syndrome). Conclusions: In conclusion, NLCS is rare and benign condition, which should be differentiated from other malignant skin condi- tions as it is commonly misdiagnosed. Therefore, physicians and surgeons should be aware of its clinical and histopathological features.

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References

  1. Hoffmann E, Zurhelle E. Über einen Naevus lipomatodes cutaneus superficialis der linken Glutaalgegend. Archiv fur Dermatologie und Syphilis. 1921;130(1):327-33. doi: 10.1007/bf01826150.
  2. Goucha S, Khaled A, Zeglaoui F, Rammeh S, Zermani R, Fazaa B. Nevus lipomatosus cutaneous superficialis: Report of eight cases. Dermatol Ther (Heidelb). 2011;1(2):25-30. doi: 10.1007/s13555-011-0006-y. [PubMed: 22984661]. [PubMed Central: PMC3437641].
  3. Ranjkesh MR, Herizchi QH, Yousefi N. Nevus lipomatosus cutaneous superficialis: A case report with histologic findings. J Turk Acad Dermatol. 2009;3(1):93103c.
  4. Ross CM. Generalized folded skin with underlying lipomatous nevus: the Michelin Tyre baby. Arch Dermatol. 1972;106(5):766. [PubMed: 4635809].
  5. Bass HN, Caldwell S, Brooks BS. Michelin tire baby syndrome: familial constriction bands during infancy and early childhood in four generations. Am J Med Genet. 1993;45(3):370-2. doi: 10.1002/ajmg.1320450318. [PubMed: 8434626].
  6. Gardner EW, Miller HM, Lowney ED. Folded skin associated with underlying nevus lipomatosus. Arch Dermatol. 1979;115(8):978-9. [PubMed: 464627].
  7. Cardot-Leccia N, Italiano A, Monteil MC, Basc E, Perrin C, Pedeutour F. Naevus lipomatosus superficialis: A case report with a 2p24 deletion. Br J Dermatol. 2007;156(2):380-1. doi: 10.1111/j.1365-2133.2006.07622.x. [PubMed: 17223884].
  8. Triki S, Mekni A, Haouet S, Mokni M, Kchir N, Ben Osman Dhahri A, et al. [Nevus lipomatosus cutaneous superficialis: A clinico-pathological study of 13 cases]. Tunis Med. 2006;84(12):800-2. French. [PubMed: 17288284].
  9. Dotz W, Prioleau PG. Nevus lipomatosus cutaneus superficialis. A light and electron microscopic study. Arch Dermatol. 1984;120(3):376-9. [PubMed: 6231000].
  10. Chopra R, Al Marzooq YM, Siddiqui FA, Aldawsari S, Al Ameer A. Nevus lipomatosus cutaneous superficialis with focal lipocytic pagetoid epidermal spread and secondary calcinosis cutis: A case report. Am J Dermatopathol. 2015;37(4):326-8. doi: 10.1097/DAD.0000000000000118. [PubMed: 25014105].
  11. Dhamija A, Meherda A, D'Souza P, Meena RS. Nevus lipomatosus cutaneous superficialis: An unusual presentation. Indian Dermatol Online J. 2012;3(3):196-8. doi: 10.4103/2229-5178.101819. [PubMed: 23189254]. [PubMed Central: PMC3505429].
  12. Takegawa M, Kakudo N, Morimoto N, Hihara M, Masuoka H, Kusumoto K. Giant nevus lipomatosus cutaneous superficialis on the buttock. Plast Reconstr Surg Glob Open. 2018;6(11). e1918. doi: 10.1097/GOX.0000000000001918. [PubMed: 30881777]. [PubMed Central: PMC6414102].
  13. Holtz KH. [Histology of naevus lipomatodes cutaneous superficialis (Hoffmann-Zurelle)]. Arch Klin Exp Dermatol. 1955;199(3):275-86. German. [PubMed: 14388675].
  14. Sardana K, Bansal S, Garg VK, Khurana N. Treatment of Nevus lipomatosus cutaneous superficialis with CO2 laser. J Cosmet Dermatol. 2017;16(3):333-5. doi: 10.1111/jocd.12327. [PubMed: 28317240].
  15. Kim HS, Park YM, Kim HO, Lee JY. Intralesional phosphatidylcholine and sodium deoxycholate: A possible treatment option for nevus lipomatosus superficialis. Pediatr Dermatol. 2012;29(1):119-21. doi: 10.1111/j.1525-1470.2011.01413.x. [PubMed: 22150229].