The Crystallography of SARS-CoV-2 Suggests Its Deactivation


Macromolecular Drug Pharmacy

How to Cite

Fathi , M. B. (2020). The Crystallography of SARS-CoV-2 Suggests Its Deactivation. Iranian Red Crescent Medical Journal, 22(3). Retrieved from


Background: The materials science may come to assist pharmacists to fabricate new drugs for coronavirus disease 2019 (COVID-19).

Objectives: The geometrical structure of elements on the surface of severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) is analyzed to illustrate some hints about the possible choosing the factors captivating the surface of SARS-CoV-2.

Methods: The crystallographic classes and their sub-structures can be indicative of practical selection of macromolecules in drug pharmacy.

Results: The macromolecular structures with hexagonal and its sub-structures are suggested for pharmacists to probe a novel drug for COVID-19.

Conclusions: Any progress in the field of fabricating macromolecular drugs for COVID-19 is strongly dependent on finding the hexagonal and its sub-structures such as triangular and rhombus geometries.



  1. Li Q, Guan X, Wu P, Wang X, Zhou L, Tong Y, et al. Early transmission dynamics in Wuhan, China, of novel coronavirus-infected pneumonia. New Engl J. 2020;19(13):1199-207. doi: 10.1056/NEJMoa2001316. [PubMed: 31995857].
  2. Menachery VD, Yount B, Jr, Debbink K, Agnihothram S, Gralinski LE, Plante JA, et al. A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence. Nat Med. 2015;21(12):1508-13. doi: 10.1038/nm.3985. [PubMed: 26552008]. [PubMed Central: PMC4797993].
  3. Baron. Medical microbiology. 4th ed. Galveston (TX): University of Texas Medical Branch at Galveston; 1996.
  4. The Editors of Encyclopaedia Britannica. Coronavirus. Chicago, Illinois, U.S: Encyclopaedia Britannica, inc; 2020.
  5. Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, et al. A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med. 2020;382(8):727-33. doi: 10.1056/NEJMoa2001017. [PubMed: 31978945].
  6. UIC. Coronavirus disease 2019 (COVID-19). 2020, [cited 2020 Mar 09]. Available from:
  7. Sugiyama K, Amano Y. Morphological and biological properties of a new coronavirus associated with diarrhea in infant mice. Arch Virol. 1981;67(3):241-51. doi: 10.1007/bf01318134. [PubMed: 7224861]. [PubMed Central: PMC7086767].