Effect of cow colostrum, mare milk, and human milk on the viability of lung healthy and cancer cell lines




Cell viability
Cow milk
Human milk
Mare milk

How to Cite

Bursalioglu, E. O. (2021). Effect of cow colostrum, mare milk, and human milk on the viability of lung healthy and cancer cell lines. Iranian Red Crescent Medical Journal, 23(5). https://doi.org/10.32592/ircmj.2021.23.5.409 (Original work published May 18, 2021)


This study investigated the effects of lyophilized mare milk, human milk, and cow colostrum on both human lung cancer cell lines, called A549, and healthy lung cell lines, called MRC5. Mare milk, human milk, and cow colostrum varieties were applied to 6 replicates in both cell lines with lyophilized milk concentrations ranging from 50-3,200 ppm. The cell viability was monitored by optic microscopy and determined by the MTT test. ANOVA and Duncan's multiple range tests were used to analyze data. The results of this study indicated that the most effective milk type on reducing the A549 lung cancer cell line was human milk, followed by mare milk; however, cow colostrum showed little effect. It was observed that human milk and mare milk had anti-proliferative effects on lung cancer cell line at concentrations which were non-toxic to healthy lung cell line.




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