Background: Few studies have investigated the changes in postoperative quality of life; serum Livin, epidermal growth factor (EGF), and IL-8 levels; and traumatic stress in patients with early gastric carcinoma after endoscopic submucosal dissection.
Objectives: We aimed to determine the effect of endoscopic submucosal dissection on postoperative life satisfaction and serum Livin, EGF, and IL-8 levels in early gastric carcinoma patients.
Methods: Seventy-three early gastric carcinoma patients were divided into the control (n = 35) and observation (n = 38) groups based on surgical approaches and were retrospectively analyzed.
Results: The operative time, gastrointestinal recovery time, length of hospital stay, perioperative bleeding, EQ-VAS scores, GAS and MTL levels were significantly superior to those in the control group, whereas serum Livin, EGF, IL-8 and CRP levels as well as the total incidence of postoperative complications were significantly lower in the observation group than in the control group (all P < 0.05).
Conclusion: Endoscopic submucosal dissection in early gastric carcinoma patients provides the advantages of a short operative time, less perioperative bleeding, rapid postoperative recovery, and less traumatic stress and postoperative complications as well as reduced serum Livin, EGF, IL-8, and tumor marker levels.
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