Use of Chinese Visible Human (CVH) images to enhance interpretation of CT or MRI images: application to nasopharyngeal structures segmentation in Treatment Planning System (TPS)


B-spline, Mutual information, Image registration fusion, Nasopharyngeal carcinoma, Treatment Planning System


How to Cite

Yang, J., Zhang, X., Luo, B., Liu, H., Xu, Z., Wang, H., Hu, X., Sun, J., Qiao, L., Zhang, S., & Wu, Y. (2022). Use of Chinese Visible Human (CVH) images to enhance interpretation of CT or MRI images: application to nasopharyngeal structures segmentation in Treatment Planning System (TPS). Iranian Red Crescent Medical Journal, 24(10). Retrieved from


Background: With a leading morbidity among the malignant tumors in otorhinolaryngology, Nasopharyngeal carcinoma (NPC) is one of the most frequent malignant tumors in China.

Objective: To help radiotherapy doctors recognize and segment the nasopharyngeal organs in risk of Nasopharyngeal carcinoma (NPC) and make radiotherapy plan.

Methods: We used B-spline and mutual information to transform, register and fuse the Chinese Visible Human (CVH) images with the patient's personalized CT images, and integrated them into the Treatment Planning System (TPS). Consequently, Three-Dimensional Visualization Treatment Planning System (3DV+TPS) was created. To verify it, 3DV+TPS was deployed to identify and segment the nasopharyngeal organs in risk of NPC, and a questionnaire was filled out by radiotherapy doctors.

Results: Result shows that 3DV+TPS can finish registration and fusion of 4 sets of sectional anatomical images and individual CT images of patients in approximately 3 minutes and 50 seconds.

Conclusion: The registered and fused images can accurately reflect the position, outline and adjacent space of the nasopharyngeal structure which is not clear in the CT images. Thus, it is helpful for recognizing and segmenting neural, muscular and glandular structures. Through automatically registering and fusing of color images and CT gray images, 3DV+TPS improves the accuracy and efficiency of recognizing nasopharyngeal structures in making radiotherapy plan, and it is useful to improve the teaching quality of tumor radiotherapy for medical students and interns as well.


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