Pancreatic Cancer in Southern Iran

AUTHORS

N Ahmadloo 1 , F Bidouei 1 , Sh Omidvari 1 , M Ansari 1 , A Mosalaei 1 , M Mohammadianpanah 2 , *

1 Department of Radiation Oncology, Shiraz University of Medical Science, Fars, Iran

2 Department of Radiation Oncology, Nemazee Hospital, Shiraz University of Medical Sciences, Postcode: 71936-13311, [email protected], Fars, Iran

How to Cite: Ahmadloo N, Bidouei F, Omidvari S, Ansari M, Mosalaei A, et al. Pancreatic Cancer in Southern Iran, Iran Red Crescent Med J. Online ahead of Print ; 12(6):624-630.

ARTICLE INFORMATION

Iranian Red Crescent Medical Journal: 12 (6); 624-630
Article Type: Research Article
Received: January 10, 2010
Accepted: May 24, 2010

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Abstract

Background: Pancreatic cancer is still a health problem worldwide. The present study aimed to report the clinical characteristics, prognostic factors and treatment outcomes of 55 cases of pancreatic cancer and the literature review and analysis.

 

Methods: Between 1998 and 2008, 55 consecutive patients proven pathologically with adenocarcinoma of the pancreas and treated at our institution were enrolled. To find out the recent major series, a literature review was performed. We selected 35 major series including 257950 patients with pancreatic cancer for discussing the present study.

 

Results: Twenty-four patients (44%) had resectable disease, 19 (34%) had locally advanced disease, and 12 (22%) had metastatic disease. There were 22 women and 33 men ranging in age from 16 to 76 years, with a median age of 57 years at diagnosis. After a median follow-up of 15 months (range=2-104 months) for surviving patients, 14 patients were alive and without disease, 3 patients were alive with disease and 38 patients had died due to disease. The 5-year overall survival was 27%.

 

Conclusions: In this study and by analyzing the large data collection of recent major reported series, we found that pancreatic cancer tended to present at advanced stage, with a high frequency of locoregional and distant failure and a poor outcome. More effective local and systemic treatment for improving overall survival is needed.

Keywords

Pancreatic cancer Chemotherapy Radiotherapy Surgery Chemoradiation Iran

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