Thalassemia, Iron and G6PD Deficiency in Lor Migrating Nomad Children, Southern Iran

AUTHORS

M Karimi 1 , D Mehrabani 2 , * , M Pasalar 1 , AR Afrasiabi 1 , Z Mehravar 1 , I Reyhani 1 , R Hamidi 1

1 Hematology Research Center, Nemazee Hospital, Shiraz University of Medical Sciences, Fars, Iran

2 Assistant Professor of Gastroenterohepatology Research Center, Nemazee Hospital, Shiraz University of Medical Sciences, Fars, Iran

How to Cite: Karimi M, Mehrabani D, Pasalar M, Afrasiabi A, Mehravar Z, et al. Thalassemia, Iron and G6PD Deficiency in Lor Migrating Nomad Children, Southern Iran, Iran Red Crescent Med J. Online ahead of Print ; 12(4):441-445.

ARTICLE INFORMATION

Iranian Red Crescent Medical Journal: 12 (4); 441-445
Article Type: Research Article
Received: October 10, 2009
Accepted: February 8, 2010

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Abstract

Background: Ferropenia and consequent iron deficiency anemia (IDA), β-thalassemia, and glucose 6-phosphate dehydrogenase (G6PD) deficiency are three main common hematologic problems in Iran. This study was conducted on the prevalence of these problems in Lor migrating nomads ethnic group in southern Iran.

 

Methods: From June to October 2006, the blood samples of 79 Lor migrating nomadic children including 53 (67.1%) male and 26 (32.9%) female were checked for iron indices and G6PD deficiency. The family history of  favism, thalassemiaand, signs and symptoms in relation to anemia of participants were evaluated. RBC count, different types of Hb, Hct, MCV, MCH, MCHC, RDW, SI, TIBC and SF were determined immediately after blood sampling.

 

Results: Fourteen (17.7%) children had SF

 

Conclusion: Although IDA figure is less than those reported in other developing countries (25-35%); but it shows that Lor tribes in southern Iran are still behind the health status of developed countries (5-8%). Even the prevalence of β-thalassemia is not very high, but regarding the devastating potential risk of Cooley's anemia; a careful performance of Iranian thalassemia program is recommended. It seems that G6PD deficiency is prevalent in Lor nomads, so establishment of educational programs and investigation on their dietary habits seem to be a good way to prevent the favism occurrence.

Keywords

Frequency Iron deficiency Thalassemia G6PD deficiency Nomads Iran

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