Treatment of Oral Inflammatory Diseases with a New Mu-coadhesive Prednisolone Tablet Versus Triamcinolone Acetonide Paste

AUTHORS

Jannan Ghabanchi 1 , * , R Bahri Najafi 2 , S Haghnegahdar 2

1 Assistant Professor of Department of Oral Medicine, Faculty of Dentistry, Shiraz University of Medical Sciences, [email protected], Fars, Iran

2 Department of Pharmacology,Shiraz University of Medical Sciences, Fars, Iran

How to Cite: Ghabanchi J, Bahri Najafi R, Haghnegahdar S. Treatment of Oral Inflammatory Diseases with a New Mu-coadhesive Prednisolone Tablet Versus Triamcinolone Acetonide Paste, Iran Red Crescent Med J. Online ahead of Print ; 11(2):155-159.

ARTICLE INFORMATION

Iranian Red Crescent Medical Journal: 11 (2); 155-159
Article Type: Research Article
Received: September 23, 2008
Accepted: February 2, 2009

Crossmark

CHEKING

READ FULL TEXT
Abstract

Background: The existing clinical trials have shown that topical corticosteroids are often effective in the management of oral inflammatory diseases. The purpose of this study was to compare the effectiveness and safety of a new mucoadhesive prednisolone tablet with that of triamcinolone acetonid paste in the management of oral lesions such as RAS-EM -pemphigus vulgaris-recurrent intraoral herpes -OLP and chemical burn.

 

Methods: In this randomized comparative study, 60 consecutive patients with oral lesions were recruited. The patients were divided into 2 groups, one receiving topical triamcinolone acetonid 0.1% paste and the other prednisolone 5 mg mucoadhesive tablet for 2 weeks.

 

Results: The profiles of mean lesion sizes and mean pain measures did not show any difference between the prednisolone and triamcinolone groups.

 

Conclusion: It was found that prednisolone 5mg table is useful as triamcinolone paste in the treatment of oral inflammatory lesions with minimal side effects.

Keywords

Treatment Oral inflammatory diseases Prednisolone Triamcinolone acetonide

© 0, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

Full Text

Full text is available in PDF

COMMENTS

LEAVE A COMMENT HERE: