Document Type : Case reports


Department of Otolaryngology, Alanya Alaaddin Keykubat University, Antalya, Turkey


Background: Spindle cell carcinoma (sarcomatoid carcinoma) is a rare carcinoma that accounts for 2-3% of all laryngeal malignancies. Here, we present a case with laryngeal tumor diagnosed as Spindle cell carcinoma.
Case Presentation: Fifty-nine-year-old male patient was admitted to our clinic with the complaint of hoarseness and shortness of breath that has been increasing for 10 months. Indirect laryngoscopy performed on the patient, and a polypoid lesion was detected in the anterior of the left vocal cord. The patient was admitted to our clinic for direct laryngoscopy and the lesion was completely excised from the base. The case was diagnosed as "sarcomatoid carcinoma in histopathological examination.
Conclusion: Sarcomatoid carcinoma is usually diagnosed and treated at an early stage. So, it has a good prognosis. However, it has a poor prognosis in the advanced stage.


  1. Gamez ME, Jeans E, Hinni ML, Moore E, Young G, Ma D, at al. Outcomes and patterns of failure of sarcomatoid carcinoma of the larynx: The Mayo Clinic experience. Laryngoscope. 2018;128(2):373-7. doi: 10.1002/lary.26725. [PubMed: 28681992].
  2. Kumar V, Cotran RS, Robbins SL. Robbins Pathologic Basic Pathology. 6th ed. Philadelphia: WB Saunders Company, 2000. P:437.
  3. Rosai J. Ackerman's surgical pathology. 9th ed. China: Elsevier; 2004.
  4. Hellquist H, Olofsson J. Spindle cell carcinoma of the larynx. APMIS. 1989;97(7):1103-13 doi: 10.1111/j.1699-0463.1989.tb00524.x
  5. Olsen KD, Lewis JE, Suman VJ. Spindle cell carcinoma of the larynx and hypopharynx. Otolaryngol Head Neck Surg. 1997;116(1):47-52. doi: 10.1016/s0194-5998(97)70351-6. [PubMed: 9018257].
  6. Rosko AJ, Birkeland AC, Wilson KF, Muenz DG, Bellile E, Bradford CR, et al. . Tumor biomarkers in spindle cell variant squamous cell carcinoma of the head and neck.
  7. Otolaryngol Head Neck Surg. 2016;155(1):106-12. doi: 10.1177/0194599816636612. [PubMed: 26980915].
  8. Völker HU, Scheich M, Höller S, Ströbel P, Hagen R, Müller-Hermelink HK, Eck M. Differential diagnosis of laryngeal spindle cell carcinoma and inflammatory myofibroblastic tumor–report of two cases with similar morphology. Diagn Pathol. 2007;2(1):1-7. doi: 10.1186/1746-1596-2-1. [PubMed: 17212821].
  9. Ballo MT, Garden AS, El‐Naggar AK, Gillenwater AM, Morrison WH, Goepfert H, et al. Radiation therapy for early stage (T1‐T2) sarcomatoid carcinoma of true vocal cords: outcomes and patterns of failure. Laryngoscope. 1998;108(5):760-3. doi: 10.1097/00005537-199805000-00024. [PubMed: 9591559].
  10. Thompson LDR, Wieneke JA, Miettinen M at al. Spindle cell (sarcomatoid) carcinomas of the larynx : a clinicopathologic study of 187 cases. Am J Surg Pathol. 2002;26(2):153-70. doi: 10.1097/00000478-200202000-00002. [PubMed: 11812937].