A comparison of the antidotal effects of three oximes against an organophosphate on chick skeletal muscle

Gholamreza Reza Poorheidari; Mahdi Mashhadi Akbar Boojar

Volume 23, Issue 4 , 2021

  Background: One of the most toxic effects of organophosphorus poisoning (OP) is the paralysis of skeletal muscles. The oximes are a group of available antidotes. This study investigated the effects of different concentrations of paraoxon on the function of skeletal muscle and reversal or prevention of ...  Read More

A Comparison between Neuromuscular Effects of Parathion and Paraoxon on Chick Biventer Cervicis Nerve-Muscle and the Reversal of their Effects by Pralidoxime

Gholamreza Poorheidari; Alireza Shahriary; Mahdi Mashhadi Akbar Boojar

Volume 23, Issue 2 , 2021

  Background: It is generally believed that the anticholinesterase effect is induced by the organophosphate insecticide parathion only through its bioactive metabolite (i.e., paraoxon) that is created in the liver.      Objectives: This study aimed to evaluate the intrinsic anticholinesterase ...  Read More