Impact of Parents Cancer on Family Communication Models from Adolescents' Perspective

Mehrdad Azarbarzin; Amin Jafari

Volume 25, Issue 10 , 2023

  Background: Cancer is a common and fatal disease that affects family members, especially adolescents, and causes changes in family communication patternsObjectives: To investigate the impact of parental cancer on family communication patterns from the adolescents' perspective.Methods: The present study ...  Read More

Comparative Study of Catheter Structure Types on Venous Thrombosis in Cancer Patients with Peripherally Inserted Central Catheters

Xin Zhang; XinXin Yin

Volume 25, Issue 9 , 2023

  Background: Cancer patients with peripherally inserted central catheters (PICCs) are prone to venous thrombosis, occlusion, and other complications due to the disease itself, chemotherapy, age, and other factors.Objectives: The present study aimed to assess the effect of different catheter materials ...  Read More

Spotlight on the Expanding Role of DANCR in Tumorigenesis and Tumor Progression

Milad Rafat; Masoumeh Afsa; Mohsen Nikbakht; Kianoosh Malekzadeh

Volume 25, Issue 6 , 2023

  Context: Long non-coding RNA (lncRNA) is a novel set of non-coding RNAs (ncRNA), over 200 nucleotides in length, accounting for the regulation of genes and chromosome structure. There are a few articles, mostly focusing on changes in the expression profile of DANCR. However, this review tried to collect ...  Read More

Cancer and COVID-19: A Double Burden on the Healthcare System

?Ali Qasemi; Milad Lagzian; Zeynab Bayat

Volume 25, Issue 2 , 2023

  The COVID-19 pandemic has placed an unprecedented burden on the healthcare system. In particular, the intersection of COVID-19 and cancer has created a double burden on the healthcare system, presenting challenges in both the diagnosis and treatment of cancer. During the pandemic, overcrowding of hospitals ...  Read More

Improvement of Cancer Treatment Processes and Reduction of Cost and Patient Length of Stay in Hospital

Zain al-Abedin Rouhani; Hamed Kazemipoor; Alireza Mir Mohammad Sadeghi; Mohammad Fallah

Volume 24, Issue 9 , 2022

  Background: Reducing patient length of stay (LOS) in hospitals reduces the high cost of chemotherapy and increases patient satisfaction. Objectives: This study aimed to present a combined model based on value engineering and the house of quality (HOQ) to improve the chemotherapy processes of hospitalized ...  Read More

Warning of the COVID-19 Novel Variant: Is the COVID-19 Omicron Variant a Real Danger for Cancer Patients or Not?

AmirAli Moodi Ghalibaf; Mina AkbariRad; Mehdi Ataee Karizmeh

Volume 24, Issue 6 , 2022

  In late December 2019, the novel coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first presented in the Hubei province of China as pneumonia of unknown cause, which has caused millions of deaths up to now (1). Studies indicated the most common ...  Read More

Upregulation of miR-21 and miR-106b in Plasma and Tissues as a Possible Prognostic Marker in Aggressive Breast Cancer

Andia Seyedi Moghaddam; Mahdieh Salimi; Najmeh Ranji; Hossein Mozdarani

Volume 23, Issue 10 , 2021

  Background: The miRNAs are referred to small non-coding RNAs (consisting of 18 to 25 nucleotides). Functional studies have shown their functions to be oncogenes or tumor suppressor genes in different types of cancers. The miR-106b and miR-21 have been identified to participate in the biological behaviors ...  Read More

Effect of Melatonin on Reversing Multidrug Resistance by Targeting Phosphatase and Tensin Homolog in Leukemia Cancer Cells

Vahid Rameshknia; Moireh Movahhedi; Abbas Akhavan; Maryam Majidinia; Bahman Yousefi

Volume 23, Issue 7 , 2021

  Background: Recently, melatonin has attracted massive attention due to its anticancer effect on various human malignancies. It has also been demonstrated that melatonin is useful in combating resistance against conventional chemotherapeutics. Objectives: This study aimed to evaluate melatonins effects ...  Read More

Quercetin Increases Doxorubicin-Induced Apoptosis Through Oxidative DNA Damage in KATO III Gastric Cancer Cells

Mingxiang Chen; Chunxiao Duan; Jun Pan

Volume 23, Issue 4 , 2021

  Background: Gastric cancer is the most common gastrointestinal malignancy with an increasing incidence rate worldwide. Finding novel curative and preventive approaches that could target the tumor cells without affecting the normal cells and overcome drug resistance will be tremendously useful. Objectives: ...  Read More

Promotion of Extrinsic Apoptosis Pathway in HCT-116 Human Colorectal Cancer Cell Line by Sodium Butyrate as Histone Deacetylase Inhibitor

Ainaz Mashayekhi; Flora Forouzesh; Mohammadreza Mashayekhi

Volume 23, Issue 1 , 2021

  Background: Colorectal cancer (CRC) has already been considered the fourth leading cause of mortality worldwide as the genes involved in apoptotic pathways and alterations of reversible epigenetic have an important role in the progression of CRC.      Objectives: The current study ...  Read More

Evaluation of Oncological Hyperthermia Centers and Turkey Modeling Oncological Hyperthermia Centers and Turkey Modeling

Fatih Goksel; Fatih Demircioglu

Volume 22, Issue 12 , 2020

  Introduction and Objectives: The latest technology and current treatments are used in the treatment of cancer in Turkey; however, oncological hyperthermia devices are currently not available. This study aimed to demonstrate the necessity of oncological hyperthermia devices in Turkey where cancer treatment ...  Read More

An Unusual Ring-Shaped Gallstone Mimicking Porcelain Gallbladder in a Patient with Chronic Kidney Disease: A Case Report

Shang-Feng Tsai; Jun-Li Tsai

Volume 21, Issue 3 , 2019, Pages 1-4

  Background: Porcelain gallbladder is associated with a higher prevalence of malignancy. Prophylactic cholecystectomy is sug-gested for both symptomatic and asymptomatic patients. Although gallstones are very commonly observed in clinical practices, itis recommended in asymptomatic patients. However, ...  Read More

Anti-Proliferative Effects of Two New Lactobacillus Strains of Human Origin on Caco-2 Cell Line

Simin Arian; Hami Kaboosi; Zaheir Heshmatipour; Zeinab Khazaei Koohpar; Fatemeh Pyravii-Ghadikolaii

Volume 21, Issue 3 , 2019, Pages 1-8

  Background: Anti-proliferative effects of probiotics are considerable in the treatment of various cancers, including colon cancer. In the present study, two new Lactobacillus strains as probiotics were isolated from stool samples at a clinical lab.Objectives: The aim of this study was to evaluate the ...  Read More

Cross-Sectional Study of Gene Expression Analysis Identifies Critical Biological Pathways and Key Genes Implicated in Non-Small Cell Lung Cancer

Tonglian Wang; Jing Hu; Lutong Xu; Hongbo Zhao; Yuanyue Li; Tao Shou; Xueshan Xia; Qiang Chen

Volume 20, Issue 3 , 2018, Pages 1-9

  Background: Non-small cell lung cancer (NSCLC) is the most common type of lung Neoplasms, which accounts for about 85% of all lung cancer types. However, critical biological pathways and key genes implicated in NSCLC remain ambiguous. Objectives: The present study aimed at identifying the critical biological ...  Read More

RNAi-Mediated Knockdown of Skp2 Inhibits Human Bladder Cancer Proliferation and Invasion in T24 Cells

Song-Tao Xu; Jun-ping xiong; Guo-Jian Gu; Song Meng; Yong-Chao Ma

Volume 19, Issue 1 , 2017, Pages 1-6

  Background: Skp2 (S-phase kinase-associated protein 2 is overexpressed in many kinds of cancers, and is related to the occurrence and development of tumors. The molecular mechanism of Skp2 in the regulation of bladder cancer cell biological behavior after Skp2 expression knockdown, however, has remained ...  Read More