A woman with Clostridium tetani infection and metastatic breast cancer: A case report

Aria Kasiri; Mahdi Baladieh; Shiva shabani; Majid Akbari

Volume 25, Issue 11 , 2023

  Tetanus could be a genuine and possibly dangerous neurological infection caused by the tetanus poison delivered by the bacterium Clostridium tetani. Infection occurs through contaminated wounds, burns, surgical wounds, and insect bites. Related symptoms include muscle spasms, autonomic instability, and ...  Read More

In Silico and Experimental Outcomes of the Expression of miR508-5p and miR-635 in Tumor Tissues of Patients with Breast Cancer

Fatemeh Zeinali Sehrig; Mohammad Zaefizadeh; Changiz Ahmadizadeh; Mohammad Reza Alivand; Saeid Ghorbian

Volume 25, Issue 8 , 2023

  Background: Breast cancer (BC) is a malignant tumor that occurs in the epithelial tissue of the breast gland and has become the most common malignancy in women. Various studies have reported the effect of epigenetic changes, including DNA methylation and microRNAs, on breast carcinogenesis. microRNAs ...  Read More

Efficacy and Safety of Immediate Latissimus Dorsi Breast Reconstruction after Breast Cancer Surgery

Xiaolin Xia; Zhou Chen; Li Cao; Jie Zhou; Zhuo Chen

Volume 25, Issue 8 , 2023

  Background: Most traditional breast reconstruction surgeries require the removal of the patient's own tissue or the use of artificial implants for reconstruction. The improvement of the efficiency and safety of breast reconstruction surgery assumes critical importance for the rehabilitation of breast ...  Read More

Anti-tumor Effect of the Ethanolic Extract of Vinca herbacea on Human Breast Cancer Cell Line: A Mechanism Study

Somayeh Dehghanipour; Sara Saadatmand; Nasim Hayati Roodbari; Mahdi Mahdavi

Volume 24, Issue 8 , 2022

  Background: Breast cancer is extensively studied for its resistance to chemotherapy. Therefore, finding efficient therapeutic agents is vital to increasing the survival rate of patients. Objectives: Here, we conducted an in vitro study on the anti-tumor properties of Vinca herbacea extract on SKBR3 ...  Read More

Efficacy and Safety of Concurrent Chemoradiotherapy with Docetaxel for Locally Advanced Breast Carcinoma after Modified Radical Mastectomy

Juanni Wang; Chunyan Wei; Wei Liu; Baofeng Wang; Qiang Han

Volume 24, Issue 7 , 2022

  Background: Breast cancer is a common term for a malignant tumor that arises from the epithelial component of the breast. Concurrent chemoradiotherapys efficacy and safety are controversial, considering the impact on patients' quality of life. Objectives: The aim of this study was investigating the efficacy ...  Read More

Effect of Fear of Covid-19 Infection on Functionality in Breast Cancer Patients in the Pandemic

Emine Fusun Akyuz Cim; Esra Torlak; Gizem Unveren; Gursel Remzi Soybir; Vahit Ozmen; Zeynep ErdoGan Iyigun; Tuba Kayan Tapan; Abdullah Yesilova; Gul Alco; Ebru Yilmaz; Asli Eyrenci; Filiz Elbuken; Ahmet Serkan Ilgun; Tomris Duymaz; Cetin Ordu

Volume 24, Issue 2 , 2022

  Background: Coronavirus disease 2019 (COVID-19) has spread rapidly across the globe through coughing, sneezing, droplet inhalation, and contact. Objectives: The current study aimed to assess the impact of the fear of COVID-19 infection on functionality in women with breast cancer. Methods: The present ...  Read More

Factors Affect?ng Sentinel Lymph Node Metastasis in Patients w?th Breast Cancer Undergo?ng Sentinel Lymph Node Biopsy before or after Systemic Therapy

Mehmet Furkan Sagdic; Cemil Yuksel; Serdar Culcu; Bulent Aksel; Cihangir Ozaslan; Suat Kutun; Lutfi Dogan

Volume 23, Issue 10 , 2021

  Background: The tendency to spread to sentinel lymph node (SLN) may differ depending on the biological, clinical, and histopathological features of tumors. If the factors that affect SLN metastasis (SLNM) are known, there may be no need to perform SLN biopsy (SLNB) in some groups. Objectives: This study ...  Read More

Human papillomavirus infection and risk of breast cancer in Iran: a meta-analysis

Hassan Nourmohammadi; Sara Yousefzadeh Shoushtari; Lila Jouybari; Maryam Ghasemi; Abas Ghaysouri; Kambiz Keshavarz

Volume 23, Issue 7 , 2021

  Background: Breast cancer is the most common malignancy and a leading cause of death in women. Viruses are known to be the risk factors for breast cancer. The present study aimed to evaluate the association between human papillomavirus (HPV) and the development of breast cancer in Iranian women by a ...  Read More

Changes in Expression of miRNA-320a and miRNA-497-5p in Early Stage of Breast Cancer

Zahra Nashtahosseini; Farzin Sadeghi; mahmodreza aghamaali

Volume 23, Issue 6 , 2021

  Background: Micro-ribonucleic acids (miRNAs) are noncoding small RNA species considered a varying class with a single-stranded structure whose expression is often dysregulated in cancer. The expression of miRNAs has been used as a promising new biomarker for the detection of breast cancer (BC).   Objectives: The ...  Read More

Relationship of Breast Cancer Susceptibility with Rs6257 and Rs6258 Polymorphisms in the SHBG Gene

Sara Shirzad; zahra Tahmasebi Fard; Seyed Hamid Jamaldini

Volume 22, Issue 10 , 2020

  Background: Breast cancer is a hormone-dependent malignancy. Sex hormone-binding globulin (SHBG) is the main transport binding protein for sex steroid hormones in plasma and regulates their accessibility to target cells. Objective: The present study aimed to assess the relationship between rs6257 and ...  Read More

Intracellular Fibronectin Expression in Invasive Breast Carcinoma: Is It Related to Significant Clinicopathological Prognostic Factors?

Fereshteh Mohammadizadeh; Somayeh Heydari

Volume 22, Issue 4 , 2020

  Background: Fibronectin plays a key role in the extracellular matrix. The expression of fibronectin and its impact on tumor behavior have been studied in several tumors such as breast carcinoma. Objectives: We aimed at investigating the immunohistochemical expression of intracellular fibronectin ...  Read More