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Comparing the Effect of Phenytoin Syrup and Triamcinolone Acetonide Ointment on Aphthous Ulcers in Patients with Behcet’s Syndrome

AUTHORS

MM Fani 1 , H Ebrahimi 1 , S Pourshahidi 2 , * , S Pourshahidi 3 , E Aflaki 4

1 Department of Oral Medicine, Dental School, Shiraz University of Medical Sciences, Shiraz, Iran

2 Dentist, Shiraz University of Medical Sciences, Shiraz, Iran

3 Assistant Professor of Oral Medicine, Dental School, Shiraz University of Medical Sciences, Shiraz, Iran

4 Department of Rheumatology, Shiraz University of Medical Sciences, Shiraz, Iran

How to Cite: Fani M, Ebrahimi H, Pourshahidi S, Pourshahidi S, Aflaki E. Comparing the Effect of Phenytoin Syrup and Triamcinolone Acetonide Ointment on Aphthous Ulcers in Patients with Behcet’s Syndrome, Iran Red Crescent Med J. 2012 ; 14(2):e95931.

ARTICLE INFORMATION

Iranian Red Crescent Medical Journal: 14 (2); e95931
Published Online: February 29, 2012
Article Type: Research Article
Received: July 02, 2019
Accepted: February 29, 2012

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Abstract

Background: Recurrent aphthous stomatitis (RAS) appears to be the most common type of oral ulcers. The lesion is usually self limited but its painful presentation results in some difficulties. Therefore, an efficient therapeutic strategy is required and currently existing therapies seem to be inadequate because of its unclear etiology. Here the therapeutic effect of triamcinolone acetonide ointment as a relatively expensive medication has been compared with phenytoin syrup on aphthous ulcers in patients with Behcet’s syndrome.

 

Methods: Thirty out of 60 our patients with Behcet’s syndrome were randomly treated by phenytoin syrup and the remaining  were advised to use 0.1% triamcinolone acetonide ointment. After a week, they were visited again to determine the status of aphthous ulcers.

 

Result: Positive response in the triamcinolone acetonide  group and phenytoin  group was 86.7% and 53.3%, respectively.

 

Conclusion: The effectiveness of triamcinolone acetonide ointment was more than  phenytoin on aphthous ulcers in patients with Behcet’s syndrome. 

Keywords

Phenytoin Triamcinolone Acetonide Aphthous ulcer Behcet’s syndrome

© 2012, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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