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Tuberculosis in Patients with Anthracosis of Lung Underlying Mechanism or Superimposed Disease

AUTHORS

Majid Mirsadraei 1 , * , AK Asnashari 1 , DM Attaran 1

AUTHORS INFORMATION

1 Internist and Subspecialty in Pulmonary Medicine, Islamic Azad University, Mashhad Branch, Iran

How to Cite: Mirsadraei M, Asnashari A, Attaran D. Tuberculosis in Patients with Anthracosis of Lung Underlying Mechanism or Superimposed Disease, Iran Red Crescent Med J. 2011 ; 13(9):e95926.

ARTICLE INFORMATION

Iranian Red Crescent Medical Journal: 13 (9); e95926
Published Online: September 30, 2011
Article Type: Rapid Communication
Received: July 02, 2019
Accepted: September 30, 2011

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Abstract

Background: Anthracosis is the black pigment discoloration of bronchi with an unknown cause which can cause bronchial destruction and deformity (anthracofibrosis). The objective of this study was to determine the frequency of tuberculosis in anthracosis and evaluate their association.

 

Methods: One hundred and twenty subjects with bronchoscopy diagnosis of simple anthracosis, anthracofibrosis and non-anthracotic control groups entered this study. Demographic data and important clinical and radiological findings were recorded. Bronchial biopsy and bronchoalveolar lavage were performed for further cytopathological, acid-fast bacilli staining and culture in all cases.

 

Results: Cough and dyspnea were significantly higher in anthracosis subjects. Radiological characteristic of tuberculosis such as upper lobe localization and cavity were not significantly higher in anthracosis subjects that suffer from tuberculosisLaboratory test for tuberculosis showed positive acid fast bacilli in 17.5 and 25% and caseating granuloma in 20 and 17.5% of anthracosis and anthracofibrosis subjects. Adding the result of culture, the frequency of tuberculosis in both groups of anthracosis was 27.5% that was significantly more than non-anthracotic control group(Odd ratio= 6.15, CL=1.29<OR<40.06). 

 

Conclusion: Anthracosis and tuberculosis showed a significant association. Anti-tuberculosis therapy promised better treatment of anthracosis in subjects proved to suffer from tuberculosis.

Keywords

Anthracosis Anthracofibrosis Tuberculosis Acid fast bacilli Caseating granuloma

© 2011, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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