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The Effect of Commiphora molmol (Myrrh) in Treatment of Trichomoniasis vaginalis infection

AUTHORS

GM El-Sherbiny 1 , * , ET el Sherbiny 2

AUTHORS INFORMATION

1 Department of Parasitology, Faculty of Pharmacy, October 6 University, gody_55@yahoo.com, Egypt

2 Department of Zoology, El Nahda University, Egypt

How to Cite: El-Sherbiny G, el Sherbiny E. The Effect of Commiphora molmol (Myrrh) in Treatment of Trichomoniasis vaginalis infection, Iran Red Crescent Med J. Online ahead of Print ; 13(7):480-486.

ARTICLE INFORMATION

Iranian Red Crescent Medical Journal: 13 (7); 480-486
Article Type: Research Article
Received: September 12, 2010
Accepted: January 10, 2011

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Abstract

Background: Trichomoniasis vaginalis is now an important worldwide health problem. Metronidazole has so far been used in treatment, but the metronidazole-resistant strains and unpleasant adverse effects have been developed. Myrrh is one of the oldest known medicinal plants used by the ancient Egyptians for medical purposes and for mummification. Commiphora molmol (Myrrh) proved safe for male reproductive organ which is the main habitat of T. vaginalis and this study aims to evaluate the efficacy of the herbal against T. vaginalis in females.

Methods: In the present study, 33 metronidazole-resistant T. vaginalis females were treated with a combined course of metronidazole and tinidazole. Those still resistant to the combined treatment were given C. molmol. Also, natural plant extract purified from pomegranate (Punica granatum, Roman) was in-vitro investigated for its efficacy against T. vaginalis on Diamond media.

Results: The anti-T. vaginalis activity of both P. granatum (in-vitro) and C. molmol (in-vivo) extracts gave promising results.

Conclusion: The anti-T. vaginalis activity of P. granatum and C. molmol showed promising results indicating to sources of new anti-Ttrichomonas agents.

Keywords

Punica granatum Commiphora molmol Trichomonas vaginalis Trichomoniasis Treatment

© 0, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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