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Investigate the Role of Glutathione S Transferase (GST) Polymorphism in Development of Hypertension in UAE Population

AUTHORS

Kosar Hussain 1 , * , Neveen Salah 2 , Sahar Hussain 3 , Sara Hussain 2

AUTHORS INFORMATION

1 Rashid Hospital, Dubai Health Authority, exquisite_k1807@hotmail.com, United Arab Emirates

2 Department of Biochemistry, Dubai Medical College, United Arab Emirates

3 UAE University, Faculty of Medicine & Health Sciences, United Arab Emirates

How to Cite: Hussain K, Salah N, Hussain S, Hussain S. Investigate the Role of Glutathione S Transferase (GST) Polymorphism in Development of Hypertension in UAE Population, Iran Red Crescent Med J. Online ahead of Print ; 14(8):479-482.

ARTICLE INFORMATION

Iranian Red Crescent Medical Journal: 14 (8); 479-482
Article Type: Research Article
Received: April 14, 2012
Accepted: July 5, 2012

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CHEKING

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Abstract

Background: GST is a family of enzymes that are important in protection of the body against oxidative stress.
Objectives: Investigate the association between GSTT1 and GSTM1 polymorphism and hypertension.
Materials and Methods: GSTT1 and GSTM1 genotypes were detected by PCR. The fragments were then analyzed by agarose gel electrophoresis.
Results: There is no significant association between GSTT1 & GSTM1 polymorphism and hypertension (OR = 2.4, P > 0.05 and OR = 1.6, P > 0.05)
Conclusions: GSTT1 & GSTM1 polymorphism can be considered a risk factor for hypertension.


Please cite this paper as:
Hussain K, Salah N, Hussain S, Hussain S. Investigate the Role of Glutathione S Transferase (GST) Polymorphism in Development of Hypertension in UAE Population. Iran Red Crescent Med J.2012;14(8):479-82.

Keywords

Hypertension Glutathione S-Transferase T1 Polymorphism, Genetic

© 0, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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