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The Effects of Fumaria Parviflora L Extract on Chronic Hand Eczema: A Randomized Double-Blind Placebo Controlled Clinical Trial

AUTHORS

F Jowkar 1 , * , A Jamshidzadeh 2 , A Mirzadeh Yazdi 2 , M Pasalar 2

1 Department of Dermatology, School of Medicine, Shiraz University of Medical Sciences, jowkarf@yahoo.com, Iran

2 Department of Pharmacology and Toxicology, Faculty of Pharmacy, Shiraz University of Medical Sciences, Iran

How to Cite: Jowkar F, Jamshidzadeh A, Mirzadeh Yazdi A, Pasalar M. The Effects of Fumaria Parviflora L Extract on Chronic Hand Eczema: A Randomized Double-Blind Placebo Controlled Clinical Trial, Iran Red Crescent Med J. Online ahead of Print ; 13(11):824-828.

ARTICLE INFORMATION

Iranian Red Crescent Medical Journal: 13 (11); 824-828
Article Type: Research Article
Received: May 12, 2011
Accepted: July 4, 2011

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Abstract

Background: Hand eczema is a common and distressing condition with multiple causes such as atopy, irritant and allergic contact dermatitis. Fumaria parviflora, is known as Shahtareh in Persian, is a folk medicine for eczema. This study aimed to evaluate the effect of alcoholic extract of Fumaria parviflora on hand eczema.

 

Methods: In a randomized double-blind, placebo-controlled study, 44 patients with hand eczema were randomly assigned to apply 4% cream of Fumaria parviflora or vehicle cream to hand twice daily for 4 weeks.

 

Results: The reduction of eczema area and severity index score before and two weeks after therapy was statistically significant between vehicle treated and in treated group. Only one patient showed side effects such as erythema and population.

 

Conclusion: Fumaria parviflora appears to be tolerated by most patients and the findings showed that its extract may be considered as an effective agent for treatment of chronic hand eczema.

Keywords

Eczema Fumaria parviflora Fumaric acid

© 0, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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