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Intestinal Leishmaniasis in Acquired Immunodeficiency Syndrome

AUTHORS

M Molaei 1 , * , M Minakari 2 , Sh Pejhan 3 , R Mashayekhi 3 , AR Modaress Fatthi 3 , MR Zali 3

AUTHORS INFORMATION

1 Department of Pathology, Research Center of Gastroenterology and Liver Disease, Shaheed Beheshti University of Medical Sciences, mahhsaa@gmail.com, Tehran, Iran

2 Departments of Gastroenterology and Hepatology, Isfahan University of Medical Sciences, Iran

3 Department of Pathology, Research Center of Gastroenterology and Liver Disease, Shaheed Beheshti University of Medical Sciences, Tehran, Iran

How to Cite: Molaei M, Minakari M, Pejhan S, Mashayekhi R, Modaress Fatthi A, et al. Intestinal Leishmaniasis in Acquired Immunodeficiency Syndrome, Iran Red Crescent Med J. Online ahead of Print ; 13(5):348-351.

ARTICLE INFORMATION

Iranian Red Crescent Medical Journal: 13 (5); 348-351
Article Type: Case Report
Received: September 25, 2010
Accepted: November 10, 2010

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Abstract

In endemic regions, visceral leishmaniasis is one of the most common opportunistic infections in HIV positive patients. Simultaneous infection with Leishmania and HIV has been reported in some countries but this is the first report of such a case in Iran. Our patient was a 27 years old man with intermittent night fever, abdominal pain, loss of appetite, vomiting, watery diarrhea and severe weight loss for 6 months. He had low socio-economic status with an imprisonment history. The patient was quite cachectic and had low grade fever. Physical exam and upper GI endoscopy revealed oropharyngeal candidiasis. Microscopic evaluation of duodenal biopsy material showed Leishmania amastigotes in macrophages of lamina propria. Leishman bodies were also observed in bone marrow aspiration specimen. Serologic tests were positive for Leishmania infantum. HIV antibody was also positive with a CD4+cell count of 80/µl. The diagnosis was acquired immunodeficiency syndrome with simultaneous visceral leishmaniasis involving intestinal mucosa.

Keywords

Aids Viscerl leishmaniasis

© 0, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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