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The Effect of Fig Tree Latex (Ficus carica) on Stomach Cancer Line

AUTHORS

A Hashemi 1 , S Abediankenari 2 , * , M Ghasemi 1 , M Azadbakht 1 , Y Yousefzadeh 1 , AA Dehpour 3

AUTHORS INFORMATION

1 Department of Microbiology and Immunology, Mazandaran University of Medical Sciences, Iran

2 Assistant Professor of Immunology, Department of Microbiology and Immunology, Mazandaran University of Medical Sciences, abedianks@razi.tums.ac.ir, Iran

3 Department of Biology, Islamic Azad University, Ghaemshahr Branch, Iran

How to Cite: Hashemi A, Abediankenari S, Ghasemi M, Azadbakht M, Yousefzadeh Y, et al. The Effect of Fig Tree Latex (Ficus carica) on Stomach Cancer Line, Iran Red Crescent Med J. Online ahead of Print ; 13(4):272-275.

ARTICLE INFORMATION

Iranian Red Crescent Medical Journal: 13 (4); 272-275
Article Type: Brief Report
Received: October 9, 2010
Accepted: January 10, 2011

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Abstract

Background: The therapeutic effect of herbal materials in inhibition of cancer cell growth was shown. This study investigates the effect of fig tree latex (Ficus carica) on stomach cancer line.

Methods: The in vitro effect of different doses of fig tree latex on stomach cancer cell line and the peripheral blood mononuclear cells was evaluated after 72 hours.

 Results:  Fig tree latex could inhibit the proliferation of cancer cell line without any cytotoxic effect on human normal cells. Five mg/ml was the optimum concentration in inhibition of cell line growth.

Conclusion: Cancer cell line was more sensitive to Ficus carica latex than normal cells. This anticancer activity might be due to presence of its proteolytic enzymes. 

Keywords

Fig Ficus carica Stomach cancer cell line Latex

© 0, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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