Iranian Red Crescent Medical Journal

Published by: Kowsar

The Effects of Natural Nano-Sized Clinoptilolite and Metformin on the Levels of Serum Glucose, Lipid Profile, and Minerals in Rats with Type 2 Diabetes Mellitus

Habib Fallahnejad 1 , Hossein Omidi 1 , Sirous Khorram 2 , Mehran Mesgari 3 , Mohammad Asghari-Jafarabadi 4 and Ali Tarighat-Esfanjani 1 , *
Authors Information
1 Faculty of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Tabriz, Iran
2 Faculty of Experimental Physics, Materials Physics, Materials Science, University of Tabriz, Tabriz, Iran
3 Department of Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
4 Department of Statistics and Epidemiology, Tabriz University of Medical sciences, Tabriz, Iran
Article information
  • Iranian Red Crescent Medical Journal: October 2018, 20 (10); e74365
  • Published Online: October 9, 2018
  • Article Type: Research Article
  • Received: May 6, 2018
  • Revised: August 16, 2018
  • Accepted: August 24, 2018
  • DOI: 10.5812/ircmj.74365

To Cite: Fallahnejad H, Omidi H, Khorram S, Mesgari M, Asghari-Jafarabadi M, et al. The Effects of Natural Nano-Sized Clinoptilolite and Metformin on the Levels of Serum Glucose, Lipid Profile, and Minerals in Rats with Type 2 Diabetes Mellitus, Iran Red Crescent Med J. 2018 ; 20(10):e74365. doi: 10.5812/ircmj.74365.

Abstract
Copyright © 2018, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited
1. Background
2. Objectives
3. Methods
4. Results
5. Discussion
Acknowledgements
Footnote
References
  • 1. American Diabetes A. Diagnosis and classification of diabetes mellitus. Diabetes Care. 2010;33 Suppl 1:S62-9. doi: 10.2337/dc10-S062. [PubMed: 20042775]. [PubMed Central: PMC2797383].
  • 2. Shen GX. Oxidative stress and diabetic cardiovascular disorders: roles of mitochondria and NADPH oxidase. Can J Physiol Pharmacol. 2010;88(3):241-8. doi: 10.1139/Y10-018. [PubMed: 20393589].
  • 3. Vahid F, Shivappa N, Karamati M, Naeini AJ, Hebert JR, Davoodi SH. Association between dietary inflammatory index (DII) and risk of prediabetes: A case-control study. Appl Physiol Nutr Metab. 2017;42(4):399-404. doi: 10.1139/apnm-2016-0395. [PubMed: 28177734].
  • 4. Demoz GT, Gebremariam G, Legesse Y. The current scenario of clinical pharmacy service in the management of patients with diabetes mellitus and related complications: Review article. India J Pharm Pract. 2018;10(4):237-47. doi: 10.5530/ijopp.10.4.50.
  • 5. Roshanravan N, Alizadeh M, Hedayati M, Asghari-Jafarabadi M, Mesri Alamdari N, Anari F, et al. Effect of zinc supplementation on insulin resistance, energy and macronutrients intakes in pregnant women with impaired glucose tolerance. Iran J Public Health. 2015;44(2):211-7. [PubMed: 25905055]. [PubMed Central: PMC4401879].
  • 6. Wiernsperger N, Rapin J. Trace elements in glucometabolic disorders: An update. Diabetol Metab Syndr. 2010;2:70. doi: 10.1186/1758-5996-2-70. [PubMed: 21167072]. [PubMed Central: PMC3023745].
  • 7. Yan MK, Khalil H. Vitamin supplements in type 2 diabetes mellitus management: A review. Diabetes Metab Syndr. 2017;11 Suppl 2:S589-95. doi: 10.1016/j.dsx.2017.04.009. [PubMed: 28420574].
  • 8. Ali MK, Bullard KM, Saaddine JB, Cowie CC, Imperatore G, Gregg EW. Achievement of goals in U.S. diabetes care, 1999-2010. N Engl J Med. 2013;368(17):1613-24. doi: 10.1056/NEJMsa1213829. [PubMed: 23614587].
  • 9. Owens DR, Monnier L, Barnett AH. Future challenges and therapeutic opportunities in type 2 diabetes: Changing the paradigm of current therapy. Diabetes Obes Metab. 2017;19(10):1339-52. doi: 10.1111/dom.12977. [PubMed: 28432748]. [PubMed Central: PMC5637910].
  • 10. Ashraf H, Zare S. Preventive effects of aqueous extract of berberis integerrima bge. Root on liver injury induced by diabetes mellitus (type 1) in rats. Iran J Pharm Res. 2015;14(1):335-43. [PubMed: 25561940]. [PubMed Central: PMC4277647].
  • 11. Rashid R, Murtaza G, Khan AK, Mir S. Antioxidant and hypoglycemic effect of otostegia aucheri methanolic extract in streptozotocin-induced diabetic male long-Evans rats. Acta Pol Pharm. 2014;71(4):631-5. [PubMed: 25272889].
  • 12. Rimoli MG, Rabaioli MR, Melisi D, Curcio A, Mondello S, Mirabelli R, et al. Synthetic zeolites as a new tool for drug delivery. J Biomed Mater Res A. 2008;87(1):156-64. doi: 10.1002/jbm.a.31763. [PubMed: 18085645].
  • 13. Prvulović D, Košarčić S, Popović M, Grubor-Lajšić G. Effects of dietary hidrated aluminosilicates on growth performance and blood parameters of pigs. Cuban J Agric Sci. 2009;43(1):59-63.
  • 14. Januškevičius A, Januškevičienė G, Plungytė K. Klinoptilolitas suaugusių šunų racionuose. Vet Med Zoot. 2013;64(86). Lithuanian.
  • 15. Zarkovic N, Zarkovic K, Kralj M, Borovic S, Sabolovic S, Blazi MP, et al. Anticancer and antioxidative effects of micronized zeolite clinoptilolite. Anticancer Res. 2003;23(2B):1589-95. [PubMed: 12820427].
  • 16. Hossein-Nia B, Khorram S, Rezazadeh H, Safaiyan A, Ghiasi R, Tarighat-Esfanjani A. The effects of natural clinoptilolite and nano-sized clinoptilolite supplementation on lipid profile, food intakes and body weight in rats with streptozotocin-induced diabetes. Adv Pharm Bull. 2018;8(2):211-6. doi: 10.15171/apb.2018.025. [PubMed: 30023322]. [PubMed Central: PMC6046415].
  • 17. Hossein Nia B, Khorram S, Rezazadeh H, Safaiyan A, Tarighat-Esfanjani A. The effects of natural clinoptilolite and nano-sized clinoptilolite supplementation on glucose levels and oxidative stress in rats with type 1 diabetes. Can J Diabetes. 2018;42(1):31-5. doi: 10.1016/j.jcjd.2017.01.010. [PubMed: 28506813].
  • 18. Omidi H, Khorram S, Mesgari M, Asghari-Jafarabadi M, Tarighat-Esfanjani A. Effects of separate and concurrent supplementation of Nano-sized clinoptilolite and Nigella sativa on oxidative stress, anti-oxidative parameters and body weight in rats with type 2 diabetes. Biomed Pharmacother. 2017;96:1335-40. doi: 10.1016/j.biopha.2017.11.077. [PubMed: 29169727].
  • 19. Demirel R, Yokus B, DEMİREL DE, Ketani MA, Baran MS. Effects of dietary zeolite on serum contents and feeding performance in rats. Int J Agric Biol. 2011;13(3).
  • 20. Khataee A, Bozorg S, Khorram S, Fathinia M, Hanifehpour Y, Joo SW. Conversion of natural clinoptilolite microparticles to nanorods by glow discharge plasma: A novel fe-impregnated nanocatalyst for the heterogeneous fenton process. Ind Eng Chem Res. 2013;52(51):18225-33. doi: 10.1021/ie403283n.
  • 21. Garimella S, Seshayamma V, Rao HJ, Kumar S, Kumar U, Saheb SH. Effect of Metformin on Lipid profile of type II diabetes. Int J Intg Med Sci. 2016;3(11):449-53. doi: 10.16965/ijims.2016.155.
  • 22. Pavelic K, Hadzija M. Medical applications of zeolites. Handbook of Zeolite science and technology. New York: Dekker; 2003. p. 1143-74.
  • 23. Qiu Q, Zhang F, Zhu W, Wu J, Liang M. Copper in diabetes mellitus: A meta-analysis and systematic review of plasma and serum studies. Biol Trace Elem Res. 2017;177(1):53-63. doi: 10.1007/s12011-016-0877-y. [PubMed: 27785738].
  • 24. Siddiqui K, Bawazeer N, Joy SS. Variation in macro and trace elements in progression of type 2 diabetes. ScientificWorldJournal. 2014;2014:461591. doi: 10.1155/2014/461591. [PubMed: 25162051]. [PubMed Central: PMC4138889].
  • 25. Chakraborty A, Chowdhury S, Bhattacharyya M. Effect of metformin on oxidative stress, nitrosative stress and inflammatory biomarkers in type 2 diabetes patients. Diabetes Res Clin Pract. 2011;93(1):56-62. doi: 10.1016/j.diabres.2010.11.030. [PubMed: 21146883].
  • 26. Schwaller D, Wilkens MR, Liesegang A. Zeolite A effect on calcium homeostasis in growing goats. J Anim Sci. 2016;94(4):1576-86. doi: 10.2527/jas.2015-9690. [PubMed: 27136016].
  • 27. Thilsing-Hansen T, Jorgensen RJ, Enemark JM, Larsen T. The effect of zeolite A supplementation in the dry period on periparturient calcium, phosphorus, and magnesium homeostasis. J Dairy Sci. 2002;85(7):1855-62. doi: 10.3168/jds.S0022-0302(02)74259-8. [PubMed: 12201536].
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