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Demographic and Histological Predictors of Survival in Patients With Gastric and Esophageal Carcinoma

AUTHORS

Yousef Veisani 2 , Ali Delpisheh 3 , * , Kourosh Sayehmiri 3

AUTHORS INFORMATION

2 Department of Clinical Epidemiology, Ilam University of Medical Sciences, Ilam, IR Iran

3 Prevention of Psychosocial Injuries Department, Research Centre, Ilam, IR Iran

How to Cite: Veisani Y, Delpisheh A, Sayehmiri K. Demographic and Histological Predictors of Survival in Patients With Gastric and Esophageal Carcinoma, Iran Red Crescent Med J. Online ahead of Print ; 15(7):547-53. doi: 10.5812/ircmj.11847.

ARTICLE INFORMATION

Iranian Red Crescent Medical Journal: 15 (7); 547-53
Published Online: July 4, 2013
Article Type: Research Article
Received: April 30, 2013
Accepted: June 7, 2013
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Abstract

Background: Little is known about the possible influence of demographic and histological risk factors on the survival of patients with esophageal and gastric cancer.

Objectives: Based on the available registry and follow-up information, this study compares 1-5 year survival rate of gastric and esophageal cancer.

Patients and Methods: Through a concurrent (prospective) cohort study, all 366 patients with definite diagnosis of esophageal and gastric cancer who had been hospitalized at the Towhid Hospital, Sanandaj city, Kurdistan province, western Iran during a five-year period from 2006 onwards were recruited. The survival time of patients stratified by this method were analyzed by Kaplan-Meier analysis and Cox regression.

Results: Amongst the 366 patients, 23 had esophageal adenocarcinoma, 94 esophageal squamous-cell carcinoma and 239 had gastric adenocarcinoma. Age at diagnosis (P = < 0.001), tumor grade (P = 0.008) and practice treatment (P = < 0.001) had significant associations with the variation of survival rates in patients with esophageal but not with gastric cancer. The five-year survival rates (by year) for esophageal cancer were 49%, 27%, 24%, 22% and 19%, respectively and for gastric cancer were 41%, 17%, 13%, 10% and 5.4%, respectively.

Conclusions: Major differences between these cancers were seen in the survival rates of patients and their incidence classified by sex. Age at diagnosis and histological types were prognostic factors for survival of patients with esophageal cancer but this wasnt the case for gastric cancer.

Keywords

Gastric Cancer Esophageal Cancer Histological Factor Demographic Factor Survival

© 2013, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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