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Effectivity of One Session Charcoal Hemoperfusion Treatment in Severe Carbamazepine Poisoning

AUTHORS

Yasemin Isik 1 , * , Lokman Soyoral 2 , Sevdegul Karadas 3 , Habib Emre 4 , Muhammed Bilal Cegin 5

1 Department of Anesthesiology and Intensive Care, Medical Faculty, Yuzuncu Yil University, Van, Turkey

2 Department of Anesthesiology and Intensive Care, State Hospital, Van, Turkey

3 Department of EmergencFaculty, Yuzuncu Yil University, Van, Turkey

4 Department of Nephrology, Medical Faculty, Yuzuncu Yil University, Van, Turkey

5 Department of Anesthesiology and Intensive Care, Medical Faculty, Yuzuncu Yil University, Van, Turkey

How to Cite: Isik Y, Soyoral L, Karadas S, Emre H, Cegin M B. Effectivity of One Session Charcoal Hemoperfusion Treatment in Severe Carbamazepine Poisoning, Iran Red Crescent Med J. Online ahead of Print ; 15(8):749-751. doi: 10.5812/ircmj.7516.

ARTICLE INFORMATION

Iranian Red Crescent Medical Journal: 15 (8); 749-751
Published Online: August 4, 2013
Article Type: Case Report
Received: July 31, 2012
Accepted: July 5, 2013
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Abstract

A carbamazepine intoxication with attempt is a relatively common clinical problem that presenting with coma, respiratory depression, arrhythmia, hemodynamic instability and even death. We report a case of severe carbamazepine poisoning that was successfully treated with one session charcoal hemoperfusion. On admission, the patient was comatose and required ventilator support. Hemoperfusion with coated activated charcoal successfully decreased the serum carbamazepine concentration from 45 g mL?1 to 21 g mL?1 within 2 h, with subsequent clinical improvement.

Keywords

Carbamazepine Toxicity Hemoperfusion

© 2013, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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