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Ovarian Cyst Enlargement in a 14 Year Old Female with Persistent Ascities, Severe Hypothyroidism and Elevated Serum CA-125 Level

AUTHORS

F Motamed 1 , K Eftekhari 2 , MA Kiani 3 , * , A Rabbani 1

AUTHORS INFORMATION

1 Department of Gastroenterology, Children's Medical Center Hospital, Tehran University of Medical Sciences, Iran

2 Department of Pediatrics, Mousavi Hospital, Zanjan University of Medical Sciences, Iran

3 Department of Gastroenterology, Children's Medical Center Hospital, Dr Gharib St, Keshavarz Blvd, Kianimd@yahoo.com, Iran

How to Cite: Motamed F, Eftekhari K, Kiani M, Rabbani A. Ovarian Cyst Enlargement in a 14 Year Old Female with Persistent Ascities, Severe Hypothyroidism and Elevated Serum CA-125 Level, Iran Red Crescent Med J. Online ahead of Print ; 14(6):379-381.

ARTICLE INFORMATION

Iranian Red Crescent Medical Journal: 14 (6); 379-381
Article Type: Case Report
Received: July 10, 2011
Accepted: October 17, 2011

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Abstract

A 14 year old female complained of abdominal pain and distention with vomiting. The physical exam showed thyroid enlargement and ascites. The imaging evaluation demonstrated a large ovarian cyst. Laboratory tests depicted hypothyroidism and marked elevation of Carbohydrate antigen 125 (CA-125) levels. As the bone age was 10 years, more retarded than the chronological age, Van Wyk and Grumbach syndrome was suspected. Treatment with thyroid hormone was initiated and the condition improved dramatically with disappearance of symptoms and signs 5 weeks later.

Keywords

Ovarian cyst Hypothyroidism CA-125 Van Wyk and Grumbach syndrome

© 0, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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