Antibacterial Susceptibility Patterns and Cross-Resistance of Acinetobacter, Isolated from Hospitalized Patients, Southern Iran

AUTHORS

S Japoni 1 , * , S Farshad 2 , A Abdi Ali 3 , A Japoni 2

1 Professor Alborzi Clinical Microbiology Research Center, Nemazee Hospital, Shiraz University of Medical Sciences, japonia@hotmail.com, Iran

2 Professor Alborzi Clinical Microbiology Research Center, Nemazee hospital, Shiraz University of Medical Sciences, Iran

3 Department of Biology, Alzahra University, Iran

How to Cite: Japoni S, Farshad S, Ali A, Japoni A. Antibacterial Susceptibility Patterns and Cross-Resistance of Acinetobacter, Isolated from Hospitalized Patients, Southern Iran, Iran Red Crescent Med J. Online ahead of Print ; 13(11):832-836.

ARTICLE INFORMATION

Iranian Red Crescent Medical Journal: 13 (11); 832-836
Article Type: Brief Report
Received: March 22, 2011
Accepted: July 25, 2011

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Abstract

 

Background: Acinetobacter is a multi-drug resistant and nosocomial pathogen. The aim of this study was to determine antibacterial susceptibility patterns and cross-resistance of Acinetobacter species.

 

Methods: This study was conducted in Nemazee Hospital, Shiraz, Iran from October 2007 to September 2008. Species identification was carried out by API E20. Minimum inhibitory concentration and cross-resistance of the isolated strains to 12 antibiotics were determined by E-test method.

 

Results: Eighty eight isolates of Acinetobacter were collected from patients’ samples. Acinetobacter baumannii was isolated most frequently (79; 89.8%). Colistin, imipenem and meropenem were found to be the three most effective antibiotics with 97.7%, 77.3% and 72.7% activity against the isolates, respectively. Multi-drug resistance was revealed among 2 to 11 antibiotics and high cross-resistance was also noticed.

 

Conclusion: To alleviate the situation, strict control measures and appropriate effective antibiotic therapy should be adopted to reduce hospital costs and related mortality.

Keywords

Acinetobacter Antibiotic resistance Cross resistance Iran

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