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Seroepidemiology of Varicella Zoster Virus Infection among 1-70 year individuals in Iran

AUTHORS

M Ziyaeyan 1 , * , A Alborzi 2 , M Jamalidoust 2 , M Moieni 2 , B Pourabbas 2

1 Professor Alborzi Clinical Microbiology Research Center, Shiraz University of Medical Sciences, Nemazee Hospital, ziyaeyanm@sums.ac.ir, Fars, Iran

2 Professor Alborzi Clinical Microbiology Research Center, Shiraz University of Medical Sciences, Fars, Iran

How to Cite: Ziyaeyan M, Alborzi A, Jamalidoust M, Moieni M, Pourabbas B. Seroepidemiology of Varicella Zoster Virus Infection among 1-70 year individuals in Iran, Iran Red Crescent Med J. Online ahead of Print ; 12(2):176-180.

ARTICLE INFORMATION

Iranian Red Crescent Medical Journal: 12 (2); 176-180
Article Type: Research Article
Received: September 2, 2009
Accepted: December 14, 2009

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Abstract

Background: Varicella zoster virus (VZV) causes varicella and, later in the life of the infected person, can reactivate to cause Herpes zoster (HZ). The objective of this study was the investigation of anti Varicella zoster virus IgG antibodies in infants and adults in Shiraz, southern Iran.

 

Methods: A cross-sectional, age and population-based seroprevalence study was conducted in 2008 on 843 subjects, ages ranging from 1 to 70 years old. IgG antibodies against VZV were measured with a commercially available enzyme-linked immunosorbent assay (ELISA).

 

Results: The seroprevalence of Varicella zoster antibodies increased with age, being 25.3% in 1-5 year age group, 43.1% in 6-10 year group, 73.5% in 11-15 year group and 86% in adult population.

 

Conclusion: The majority of VZV infections occurred during childhood. The best policy to prevent the circulation of wild type VZV in the population and reduction of the rate of complicated cases is the immunization of 5 year old children and those younger. VZV vaccine should be incorporated in the conventional childhood vaccination plan in Iran.

  

Keywords

Varicella Zoster Virus Seroepidemiology Susceptibility Vaccination Iran

© 0, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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