Iranian Red Crescent Medical Journal

Published by: Kowsar

The Effect of Honey and Diet Education on Symptoms of Functional Dyspepsia: A Randomized Clinical Trial

Tarang Taghvaei 1 , Masoumeh Bagheri-Nesami 2 and Attieh Nikkhah 3,4 , *
Authors Information
1 Gut and Liver Research Center, Mazandaran University of Medical Sciences, Imam Khomeini Hospital, Sari, Iran
2 Associate Professor,Traditional and Complementary Medicine Research Center, Addiction Institute, Mazandaran University of Medical Sciences, Sari, Iran
3 Faculty of Nursing and Midwifery, Golestan University of Medical Science, Gorgan, Iran
4 Pediatric Infectious Diseases Research Center, Mazandaran University of Medical Sciences, Sari, Iran
Article information
  • Iranian Red Crescent Medical Journal: August 2018, 20 (8); e65557
  • Published Online: September 12, 2018
  • Article Type: Research Article
  • Received: December 26, 2017
  • Revised: February 10, 2018
  • Accepted: April 3, 2018
  • DOI: 10.5812/ircmj.65557

To Cite: Taghvaei T, Bagheri-Nesami M, Nikkhah A. The Effect of Honey and Diet Education on Symptoms of Functional Dyspepsia: A Randomized Clinical Trial, Iran Red Crescent Med J. 2018 ; 20(8):e65557. doi: 10.5812/ircmj.65557.

Abstract
Copyright © 2018, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited
1. Background
2. Objectives
3. Methods
4. Results
5. Discussion
Acknowledgements
Footnote
References
  • 1. Drossman DA. ROME III. The functional gastrointestinal disorders. 3rd ed. Virginia: Degnon Associates Inc. McLean; 2006.
  • 2. Mohammadalizadeh AH, Mani Kashani K, Sharafi N, Najafian M. [Comparative study of evaluation of therapeutic effects of the Thyme CW, Savory CW drops and Thyme mixture CW with Ranitidine-Metoclopramide compound in functional dyspepsia]. Avicenna j clin med. 2001;8(1):9-14. Persian.
  • 3. SaberiFiroozi M, Abedian S, Masserrat S. [Epidemiology, associated factors, and treatment experiences with dyspepsia in Iran: A review]. Govaresh. 2013;17(4):213-27. Persian.
  • 4. Lacy BE, Talley NJ, Locke GR, Bouras EP, DiBaise JK, El-Serag HB, et al. Review article: current treatment options and management of functional dyspepsia. Aliment Pharmacol Ther. 2012;36(1):3-15. doi: 10.1111/j.1365-2036.2012.05128.x. [PubMed: 22591037]. [PubMed Central: PMC3970847].
  • 5. Tack J, Talley NJ, Camilleri M, Holtmann G, Hu P, Malagelada JR, et al. Functional gastroduodenal disorders. Gastroenterology. 2006;130(5):1466-79. doi: 10.1053/j.gastro.2005.11.059. [PubMed: 16678560].
  • 6. Moayyedi P, Soo S, Deeks J, Delaney B, Innes M, Forman D. Pharmacological interventions for non-ulcer dyspepsia. Cochrane Database Syst Rev. 2006;(4). CD001960. doi: 10.1002/14651858.CD001960.pub3. [PubMed: 17054151].
  • 7. Hojo M, Miwa H, Yokoyama T, Ohkusa T, Nagahara A, Kawabe M, et al. Treatment of functional dyspepsia with antianxiety or antidepressive agents: systematic review. J Gastroenterol. 2005;40(11):1036-42. doi: 10.1007/s00535-005-1687-8. [PubMed: 16322947].
  • 8. Veldhuyzen van Zanten SJ, Jones MJ, Verlinden M, Talley NJ. Efficacy of cisapride and domperidone in functional (nonulcer) dyspepsia: a meta-analysis. Am J Gastroenterol. 2001;96(3):689-96. doi: 10.1111/j.1572-0241.2001.03521.x. [PubMed: 11280535].
  • 9. Hamilton J, Guthrie E, Creed F, Thompson D, Tomenson B, Bennett R, et al. A randomized controlled trial of psychotherapy in patients with chronic functional dyspepsia. Gastroenterology. 2000;119(3):661-9. doi: 10.1053/gast.2000.16493. [PubMed: 10982759].
  • 10. Bortolotti M, Coccia G, Grossi G, Miglioli M. The treatment of functional dyspepsia with red pepper. Aliment Pharmacol Ther. 2002;16(6):1075-82. doi: 10.1046/j.1365-2036.2002.01280.x. [PubMed: 12030948].
  • 11. Moghazy AM, Shams ME, Adly OA, Abbas AH, El-Badawy MA, Elsakka DM, et al. The clinical and cost effectiveness of bee honey dressing in the treatment of diabetic foot ulcers. Diabetes Res Clin Pract. 2010;89(3):276-81. doi: 10.1016/j.diabres.2010.05.021. [PubMed: 20646771].
  • 12. Menshikov FK, Feidman SI. [Curing stomach ulcers with honey]. Sovetskaya Meditsing. 1949;10:13-4. Russian.
  • 13. Slobodianiuk A, Slobodianiuk M. Complex treatment of gastritis patients with high stomach secretion in combination with (and without) a 15-20% solution of honey. Resort Bashkiria Serv Health. 1969:249-53.
  • 14. Salem SN. Honey regimen in gastrointestinal disorders. Bull Islamic Med. 1981;1:358-62.
  • 15. Al-Swayeh OA, Ali AT. Effect of ablation of capsaicin-sensitive neurons on gastric protection by honey and sucralfate. Hepatogastroenterology. 1998;45(19):297-302. [PubMed: 9496530].
  • 16. Nasuti C, Gabbianelli R, Falcioni G, Cantalamessa F. Antioxidative and gastroprotective activities of anti-inflammatory formulations derived from chestnut honey in rats. Nutr Res. 2006;26(3):130-7. doi: 10.1016/j.nutres.2006.02.007.
  • 17. Baltuskevicius A, Laiskonis A, Vysniauskiene D, Ceksteryte V, Racys J. [Use of different kinds of honey for hepatitis A treatment and for reduction of increased acidity of gastric juice]. Zemdirbyste Mokslo Darbai. 2001;76:173-80. Lithuanian.
  • 18. Dubtsova E. [Clinical studies with bee products for therapy of some nutritional diseases]. Cent Moscow Instit Gastroenterol Moscow. 2009:1-38. Russian.
  • 19. Castillo EJ, Camilleri M, Locke GR, Burton DD, Stephens DA, Geno DM, et al. A community-based, controlled study of the epidemiology and pathophysiology of dyspepsia. Clin Gastroenterol Hepatol. 2004;2(11):985-96. doi: 10.1016/S1542-3565(04)00454-9. [PubMed: 15551251].
  • 20. Jiang SM, Lei XG, Jia L, Xu M, Wang SB, Liu J, et al. Unhealthy dietary behavior in refractory functional dyspepsia: a multicenter prospective investigation in China. J Dig Dis. 2014;15(12):654-9. doi: 10.1111/1751-2980.12199. [PubMed: 25283636].
  • 21. Van Zanten SJOV, Tytgat KMAJ, Pollak PT, Goldie J, Goodacre RL, Riddell RH, et al. Can severity of symptoms be used as an outcome measure in trials of non-ulcer dyspepsia and Helicobacter pylori associated gastritis? J clin epidemiol. 1993;46(3):273-9.
  • 22. Boukraa L. Honey in traditional and modern medicine. CRC Press; 2013.
  • 23. Khodadad A, Khatami GR, Hatmi ZN, Karami H. [Effectiveness of combination therapy with honey in H. Pylori eradication in Pediatrics Medical Centre]. Tehran Univ Med JTUMS Publicat. 2006;64(3):78-87. Persian.
  • 24. Talley NJ, Verlinden M, Snape W, Beker JA, Ducrotte P, Dettmer A, et al. Failure of a motilin receptor agonist (ABT-229) to relieve the symptoms of functional dyspepsia in patients with and without delayed gastric emptying: a randomized double-blind placebo-controlled trial. Aliment Pharmacol Ther. 2000;14(12):1653-61. doi: 10.1046/j.1365-2036.2000.00868.x. [PubMed: 11121915].
  • 25. Ahmadi-Motamayel F, Hendi SS, Alikhani MY, Khamverdi Z. Antibacterial activity of honey on cariogenic bacteria. J Dent (Tehran). 2013;10(1):10-5. [PubMed: 23724198]. [PubMed Central: PMC3666059].
  • 26. Mohtashami R, Huseini HF, Heydari M, Amini M, Sadeqhi Z, Ghaznavi H, et al. Efficacy and safety of honey based formulation of Nigella sativa seed oil in functional dyspepsia: A double blind randomized controlled clinical trial. J Ethnopharmacol. 2015;175:147-52. doi: 10.1016/j.jep.2015.09.022. [PubMed: 26386381].
  • 27. Feinle-Bisset C, Horowitz M. Dietary factors in functional dyspepsia. Neurogastroenterol Motil. 2006;18(8):608-18. doi: 10.1111/j.1365-2982.2006.00790.x. [PubMed: 16918725].
  • 28. Carvalho RV, Lorena SL, Almeida JR, Mesquita MA. Food intolerance, diet composition, and eating patterns in functional dyspepsia patients. Dig Dis Sci. 2010;55(1):60-5. doi: 10.1007/s10620-008-0698-8. [PubMed: 19160046].
  • 29. Pilichiewicz AN, Horowitz M, Holtmann GJ, Talley NJ, Feinle-Bisset C. Relationship between symptoms and dietary patterns in patients with functional dyspepsia. Clin Gastroenterol Hepatol. 2009;7(3):317-22. doi: 10.1016/j.cgh.2008.09.007. [PubMed: 18929687].
  • 30. Saito YA, Locke GR, Weaver AL, Zinsmeister AR, Talley NJ. Diet and functional gastrointestinal disorders: a population-based case-control study. Am J Gastroenterol. 2005;100(12):2743-8. doi: 10.1111/j.1572-0241.2005.00288.x. [PubMed: 16393229].
  • 31. Cuperus P, Keeling PW, Gibney MJ. Eating patterns in functional dyspepsia: A case control study. Eur J Clin Nutr. 1996;50(8):520-3. [PubMed: 8863012].

Featured Image:

Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:

Author(s):

Article(s):

Create Citiation Alert
via Google Reader

Readers' Comments