Iranian Red Crescent Medical Journal

Published by: Kowsar

Effect of Saffron with or Without Date Sugar on Intensity of Pain and Anxiety During Labor in Primiparous Females: A Randomized, Controlled Trial

Roghayeh Mohammadierad 1 , Sakineh Mohammad-Alizadeh-Charandabi 2 , * , Mojgan Mirghafourvand 3 and Fariba Fazil 4
Authors Information
1 Students’ Research Committee, Department of Midwifery, Faculty of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, Iran
2 Social Determinants of Health Research Center, Department of Midwifery, Faculty of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, Iran
3 Department of Midwifery, Faculty of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, Iran
4 Gynecologist, 29 Bahman Hospital, Tabriz, Iran
Article information
  • Iranian Red Crescent Medical Journal: December 2018, 20 (S1); e61289
  • Published Online: May 31, 2018
  • Article Type: Research Article
  • Received: September 3, 2017
  • Revised: November 17, 2017
  • Accepted: December 20, 2017
  • DOI: 10.5812/ircmj.61289

To Cite: Mohammadierad R, Mohammad-Alizadeh-Charandabi S, Mirghafourvand M, Fazil F. Effect of Saffron with or Without Date Sugar on Intensity of Pain and Anxiety During Labor in Primiparous Females: A Randomized, Controlled Trial, Iran Red Crescent Med J. 2018 ; 20(S1):e61289. doi: 10.5812/ircmj.61289.

Abstract
Copyright © 2018, Iranian Red Crescent Medical Journal. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited
1. Background
2. Methods
3. Results
4. Discussion
Acknowledgements
References
  • 1. Jones L, Othman M, Dowswell T, Alfirevic Z, Gates S, Newburn M, et al. Pain management for women in labour: an overview of systematic reviews. Cochrane Database Syst Rev. 2012;(3). CD009234. doi: 10.1002/14651858.CD009234.pub2. [PubMed: 22419342].
  • 2. Salari P, Alavian F, Habibi-Rad A, Tara F. [The Relationship between Stress, Anxiety and Pain with Salivary Cortisol Levels in First Stage of Labor in Primiparous]. Iran J Obstet Gynecol Infertil. 2013;16(55):17-21. Persian.
  • 3. Alehagen S, Wijma B, Lundberg U, Wijma K. Fear, pain and stress hormones during childbirth. J Psychosom Obstet Gynaecol. 2005;26(3):153-65. doi: 10.1080/01443610400023072. [PubMed: 16295513].
  • 4. Azami-Aghdash S, Ghojazadeh M, Dehdilani N, Mohammadi M, Asl Amin Abad R. Prevalence and causes of cesarean section in Iran: Systematic review and meta-analysis. Iran J Public Health. 2014;43(5):545-55. [PubMed: 26060756]. [PubMed Central: PMC4449402].
  • 5. Marshall J, Raynor M. Myles Textbook for Midwives. 16th ed. London: Elsevier; 2014.
  • 6. Srivastava R, Ahmed H, Dixit RK, Saraf SA; Dharamveer. Crocus sativus L.: A comprehensive review. Pharmacogn Rev. 2010;4(8):200-8. doi: 10.4103/0973-7847.70919. [PubMed: 22228962]. [PubMed Central: PMC3249922].
  • 7. World Health Organization . WHO monographs on selected medicinal plants. 3. 2007. p. 126-35.
  • 8. Melnyk JP, Wang S, Marcone MF. Chemical and biological properties of the world's most expensive spice: Saffron. Food Res Int. 2010;43(8):1981-9. doi: 10.1016/j.foodres.2010.07.033.
  • 9. Dashti-Rahmatabadi MH, Nahangi H, Oveisi M, Anvari M. [The effect of saffron decoction consumption on pregnant mice and their offspring]. J Shaheed Sadoughi Univ Med Sci. 2012;19(6):831-7. Persian.
  • 10. Sadraei H. Effects of Zataria multiflora and Carum carvi essential oils and hydroalcoholic extracts of Passiflora incarnata, Berberis integerrima and Crocus sativus on rat isolated uterus contractions. Int J Aromather. 2003;13(2-3):121-7. doi: 10.1016/s0962-4562(03)00092-4.
  • 11. Zeinali F, Anvari M, Dashti RMH, Hosseini SM. The effects of different concentrations of saffron (Crocus sativus) decoction on preterm delivery in mice. Planta Med. 2009;75(9):1026. doi: 10.1055/s-0029-1234793.
  • 12. Poma A, Fontecchio G, Carlucci G, Chichiricco G. Anti-inflammatory properties of drugs from saffron crocus. Antiinflamm Antiallergy Agents Med Chem. 2012;11(1):37-51. doi: 10.2174/187152312803476282. [PubMed: 22934747].
  • 13. Tamaddonfard E, Farshid AA, Eghdami K, Samadi F, Erfanparast A. Comparison of the effects of crocin, safranal and diclofenac on local inflammation and inflammatory pain responses induced by carrageenan in rats. Pharmacol Rep. 2013;65(5):1272-80. doi: 10.1016/S1734-1140(13)71485-3. [PubMed: 24399723].
  • 14. Nasri S, Hosseini. S , Sahraei. H , Zardooz. H . Inhibition of pain and inflamation induced by formalin in male mice by ethanolic extract of saffron (Crocus sativus) and its constituents; crocin and safranal. Kowsar Med J. 2011;15(4):189-95.
  • 15. Hosseinzadeh H, Noraei NB. Anxiolytic and hypnotic effect of Crocus sativus aqueous extract and its constituents, crocin and safranal, in mice. Phytother Res. 2009;23(6):768-74. doi: 10.1002/ptr.2597. [PubMed: 19142981].
  • 16. Pitsikas N, Boultadakis A, Georgiadou G, Tarantilis PA, Sakellaridis N. Effects of the active constituents of Crocus sativus L., crocins, in an animal model of anxiety. Phytomedicine. 2008;15(12):1135-9. doi: 10.1016/j.phymed.2008.06.005. [PubMed: 18693098].
  • 17. Ahmadi S, Azhari S, Jafarzadeh H, Rakhshandeh J, Mazlom R. [The effect of oral capsules of saffron on anxiety and fatigue during the first stage of labor]. J Shaheed Sadoughi Univ Med Sci. 2015;23(2):1915-26. Persian.
  • 18. Boskabady MH, Aslani MR. Relaxant effect of Crocus sativus (saffron) on guinea-pig tracheal chains and its possible mechanisms. J Pharm Pharmacol. 2006;58(10):1385-90. doi: 10.1211/jpp.58.10.0012. [PubMed: 17034662].
  • 19. Azhari S, Ahmadi S, Rakhshandeh H, Jafarzadeh H, Mazlom S. [Evaluation of the effect of oral saffron capsules on pain intensity during the active phase of labor]. Iran J Obstet Gynecol Infertil. 2014;17(115):1-10. Persian.
  • 20. Sadi R, Mohammad-Alizadeh-Charandabi S, Mirghafourvand M, Javadzadeh Y, Ahmadi-Bonabi A. Effect of Saffron (Fan Hong Hua) on the readiness of the uterine cervix in term pregnancy: A placebo-controlled randomized trial. Iran Red Crescent Med J. 2016;18(10). e27241. doi: 10.5812/ircmj.27241. [PubMed: 28180016]. [PubMed Central: PMC5285732].
  • 21. Al-Alawi RA, Al-Mashiqri JH, Al-Nadabi JSM, Al-Shihi BI, Baqi Y. Date Palm Tree (Phoenix dactylifera L.): Natural products and therapeutic options. Front Plant Sci. 2017;8:845. doi: 10.3389/fpls.2017.00845. [PubMed: 28588600]. [PubMed Central: PMC5440559].
  • 22. Umar Ibrahim M, Nordin S, Abdulkareem U, Ibrahim Haruna. S , Atif Amin. B , Thant. Z . Anti-inflammatory and analgesic activities of aqueous extract date palm (phoenix dactylifera l) fruit in rats. Int J Novel Res Healthcare Nurs. 2015;2(3):166-72.
  • 23. Zangeneh F, Moezi L, Zargar A. [The effect of palm date, fig and olive fruits regimen on weight, pain threshold and memory in mice]. Iran J Med Aromatic Plants. 2009;25(2):149-58. Persian.
  • 24. Kordi M, Salek-Nasiri N, Safarian M, Esmaili H, Shadjou K. [The effect of oral honey-date syrup intake during labor on labor progress of nulliparous women]. Iran J Obstet Gynecol Infertil. 2010;13(2):23-30. Persian.
  • 25. Al-Kuran O, Al-Mehaisen L, Bawadi H, Beitawi S, Amarin Z. The effect of late pregnancy consumption of date fruit on labour and delivery. J Obstet Gynaecol. 2011;31(1):29-31. doi: 10.3109/01443615.2010.522267. [PubMed: 21280989].
  • 26. Razali N, Mohd Nahwari SH, Sulaiman S, Hassan J. Date fruit consumption at term: Effect on length of gestation, labour and delivery. J Obstet Gynaecol. 2017;37(5):595-600. doi: 10.1080/01443615.2017.1283304. [PubMed: 28286995].
  • 27. Sheikh BY, Zihad SM, Sifat N, Uddin SJ, Shilpi JA, Hamdi OA, et al. Comparative study of neuropharmacological, analgesic properties and phenolic profile of Ajwah, Safawy and Sukkari cultivars of date palm (Phoenix dactylifera). Orient Pharm Exp Med. 2016;16(3):175-83. doi: 10.1007/s13596-016-0239-5. [PubMed: 27746708]. [PubMed Central: PMC5040737].
  • 28. Elkerm Y, Tawashi R. Date palm pollen as a preventative intervention in radiation- and chemotherapy-induced oral mucositis: a pilot study. Integr Cancer Ther. 2014;13(6):468-72. doi: 10.1177/1534735414547110. [PubMed: 25148841].
  • 29. Peyghambari F, Dashti-Rahmatabadi MH, Rozabadi MD, Rozabadi RD, Rozabadi FD, Pangalizadeh M, et al. Antinociceptive effect of palm date spathe hydroalcoholic extract on acute and chronic pain in mice as compared with analgesic effect of morphine and diclofenac. Adv Biomed Res. 2015;4:244. doi: 10.4103/2277-9175.170239. [PubMed: 26693469]. [PubMed Central: PMC4685642].
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:

Author(s):

Article(s):

Create Citiation Alert
via Google Reader

Readers' Comments