Investigation of Several Biomarkers Associated with Asthmatic Chronic Rhinosinusitis with Nasal Polyps

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To Cite : Zhang Z, Yan X, Jiang J. Investigation of Several Biomarkers Associated with Asthmatic Chronic Rhinosinusitis with Nasal Polyps, Iran Red Crescent Med J. 2017 ;19(3):e41119. doi: 10.5812/ircmj.41119.
Copyright: Copyright © 2017, Iranian Red Crescent Medical Journal. .
1. Background
2. Objectives
3. Methods
4. Results
5. Discussion
  • 1. Rix I, Hakansson K, Larsen CG, Frendo M, von Buchwald C. Management of chronic rhinosinusitis with nasal polyps and coexisting asthma: A systematic review. Am J Rhinol Allergy. 2015; 29(3): 193-201[DOI][PubMed]
  • 2. Gevaert P, Calus L, Van Zele T, Blomme K, De Ruyck N, Bauters W, et al. Omalizumab is effective in allergic and nonallergic patients with nasal polyps and asthma. J Allergy Clin Immunol. 2013; 131(1): 110-6 e1[DOI][PubMed]
  • 3. Ho J, Bailey M, Zaunders J, Mrad N, Sacks R, Sewell W, et al. Group 2 innate lymphoid cells (ILC2s) are increased in chronic rhinosinusitis with nasal polyps or eosinophilia. Clin Exp Allergy. 2015; 45(2): 394-403[DOI][PubMed]
  • 4. Lengauer C, Kinzler KW, Vogelstein B. Genetic instabilities in human cancers. Nature. 1998; 396(6712): 643-9[DOI][PubMed]
  • 5. Amin SB, Yip WK, Minvielle S, Broyl A, Li Y, Hanlon B, et al. Gene expression profile alone is inadequate in predicting complete response in multiple myeloma. Leukemia. 2014; 28(11): 2229-34[DOI][PubMed]
  • 6. Plager DA, Kahl JC, Asmann YW, Nilson AE, Pallanch JF, Friedman O, et al. Gene transcription changes in asthmatic chronic rhinosinusitis with nasal polyps and comparison to those in atopic dermatitis. PLoS One. 2010; 5(7): 11450[DOI][PubMed]
  • 7. Ibanez K, Boullosa C, Tabares-Seisdedos R, Baudot A, Valencia A. Molecular evidence for the inverse comorbidity between central nervous system disorders and cancers detected by transcriptomic meta-analyses. PLoS Genet. 2014; 10(2): 1004173[DOI][PubMed]
  • 8. Christie MR, Tennessen JA, Blouin MS. Bayesian parentage analysis with systematic accountability of genotyping error, missing data and false matching. Bioinformatics. 2013; 29(6): 725-32[DOI][PubMed]
  • 9. McGibbon RT, Pande VS. Variational cross-validation of slow dynamical modes in molecular kinetics. J Chem Phys. 2015; 142(12): 124105[DOI][PubMed]
  • 10. Nibbe RK, Chowdhury SA, Koyuturk M, Ewing R, Chance MR. Protein-protein interaction networks and subnetworks in the biology of disease. Wiley Interdiscip Rev Syst Biol Med. 2011; 3(3): 357-67[DOI][PubMed]
  • 11. Davis S, Meltzer PS. GEOquery: a bridge between the Gene Expression Omnibus (GEO) and BioConductor. Bioinformatics. 2007; 23(14): 1846-7[DOI][PubMed]
  • 12. Irizarry RA, Bolstad BM, Collin F, Cope LM, Hobbs B, Speed TP. Summaries of Affymetrix GeneChip probe level data. Nucleic Acids Res. 2003; 31(4): 15[PubMed]
  • 13. Bolstad BM, Irizarry RA, Astrand M, Speed TP. A comparison of normalization methods for high density oligonucleotide array data based on variance and bias. Bioinformatics. 2003; 19(2): 185-93[PubMed]
  • 14. Huang DW, Sherman BT, Tan Q, Collins JR, Alvord WG, Roayaei J, et al. The DAVID Gene Functional Classification Tool: a novel biological module-centric algorithm to functionally analyze large gene lists. Genome Biol. 2007; 8(9)[DOI][PubMed]
  • 15. Mar JC, Matigian NA, Quackenbush J, Wells CA. attract: A method for identifying core pathways that define cellular phenotypes. PLoS One. 2011; 6(10): 25445[DOI][PubMed]
  • 16. Meyer PE, Lafitte F, Bontempi G. minet: A R/Bioconductor package for inferring large transcriptional networks using mutual information. BMC Bioinformatics. 2008; 9: 461[DOI][PubMed]
  • 17. Meyer PE, Kontos K, Lafitte F, Bontempi G. Information-theoretic inference of large transcriptional regulatory networks. EURASIP J Bioinform Syst Biol. 2007; : 79879[DOI][PubMed]
  • 18. Faith JJ, Hayete B, Thaden JT, Mogno I, Wierzbowski J, Cottarel G, et al. Large-scale mapping and validation of Escherichia coli transcriptional regulation from a compendium of expression profiles. PLoS Biol. 2007; 5(1): 8[DOI][PubMed]
  • 19. Csardi G, Nepusz T. Igraph-package. 2008;
  • 20. Koschutzki D, Schreiber F. Centrality analysis methods for biological networks and their application to gene regulatory networks. Gene Regul Syst Bio. 2008; 2: 193-201[PubMed]
  • 21. Haythornthwaite C. Social network analysis: An approach and technique for the study of information exchange. Library Information Sci Res. 1996; 18(4): 323-42
  • 22. Wolfe AW. Social network analysis: Methods and applications. American Ethnol. 1997; 24(1): 219-20[DOI]
  • 23. Barthlemy M. Betweenness centrality in large complex networks. The European Physical Journal B - Condensed Matter. 2004; 38(2): 163-8[DOI]
  • 24. Ritchie ME, Phipson B, Wu D, Hu Y, Law CW, Shi W, et al. limma powers differential expression analyses for RNA-sequencing and microarray studies. Nucleic Acids Res. 2015; 43(7): 47[DOI][PubMed]
  • 25. Smyth GK. Limma: Linear models for microarray data. 2005; : 397-420[DOI]
  • 26. Ritchie ME, Silver J, Oshlack A, Holmes M, Diyagama D, Holloway A, et al. A comparison of background correction methods for two-colour microarrays. Bioinformatics. 2007; 23(20): 2700-7[DOI][PubMed]
  • 27. Chang CC, Lin CJ. Libsvm. Acm transactions on intelligent systems and technology. 2011; 2(3): 1-27[DOI]
  • 28. Schisterman EF, Perkins NJ, Liu A, Bondell H. Optimal cut-point and its corresponding Youden Index to discriminate individuals using pooled blood samples. Epidemiology. 2005; 16(1): 73-81[PubMed]
  • 29. Naugler WE, Karin M. The wolf in sheep's clothing: the role of interleukin-6 in immunity, inflammation and cancer. Trends Mol Med. 2008; 14(3): 109-19[DOI][PubMed]
  • 30. Perrier d'Hauterive S, Charlet-Renard C, Dubois M, Berndt S, Goffin F, Foidart JM, et al. Human endometrial leukemia inhibitory factor and interleukin-6: control of secretion by transforming growth factor-beta-related members. Neuroimmunomodulation. 2005; 12(3): 157-63[DOI][PubMed]
  • 31. Reynaud D, Pietras E, Barry-Holson K, Mir A, Binnewies M, Jeanne M, et al. IL-6 controls leukemic multipotent progenitor cell fate and contributes to chronic myelogenous leukemia development. Cancer Cell. 2011; 20(5): 661-73[DOI][PubMed]
  • 32. Bradley DT, Kountakis SE. Role of interleukins and transforming growth factor-beta in chronic rhinosinusitis and nasal polyposis. Laryngoscope. 2005; 115(4): 684-6[DOI][PubMed]
  • 33. Lennard CM, Mann EA, Sun LL, Chang AS, Bolger WE. Interleukin-1 beta, interleukin-5, interleukin-6, interleukin-8, and tumor necrosis factor-alpha in chronic sinusitis: response to systemic corticosteroids. Am J Rhinol. 2000; 14(6): 367-73[PubMed]
  • 34. Danielsen A, Tynning T, Brokstad KA, Olofsson J, Davidsson A. Interleukin 5, IL6, IL12, IFN-gamma, RANTES and Fractalkine in human nasal polyps, turbinate mucosa and serum. Eur Arch Otorhinolaryngol. 2006; 263(3): 282-9[DOI][PubMed]
  • 35. Peters AT, Kato A, Zhang N, Conley DB, Suh L, Tancowny B, et al. Evidence for altered activity of the IL-6 pathway in chronic rhinosinusitis with nasal polyps. J Allergy Clin Immunol. 2010; 125(2): 397-403 e10[DOI][PubMed]
  • 36. Ferreira MA, Matheson MC, Duffy DL, Marks GB, Hui J, Le Souef P, et al. Identification of IL6R and chromosome 11q13.5 as risk loci for asthma. Lancet. 2011; 378(9795): 1006-14[DOI][PubMed]
  • 37. Brown JE, Greenberger PA, Yarnold PR. Soluble serum interleukin 2 receptors in patients with asthma and allergic bronchopulmonary aspergillosis. Ann Allergy Asthma Immunol. 1995; 74(6): 484-8[PubMed]
  • 38. Gevaert P, Holtappels G, Johansson SG, Cuvelier C, Cauwenberge P, Bachert C. Organization of secondary lymphoid tissue and local IgE formation to Staphylococcus aureus enterotoxins in nasal polyp tissue. Allergy. 2005; 60(1): 71-9[DOI][PubMed]
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