Iranian Red Crescent Medical Journal

Published by: Kowsar

The Effects of Kangaroo Mother Care and Swaddling on Venipuncture Pain in Premature Neonates: A Randomized Clinical Trial

Shahin Dezhdar 1 , Faezeh Jahanpour 2 , * , Saeedeh Firouz Bakht 3 and Afshin Ostovar 4
Authors Information
1 Bushehr University of Medical Sciences, Bushehr, IR Iran
2 Nursing and Midwifery Faculty, Bushehr University of Medical Sciences, Bushehr, IR Iran
3 Medicine Faculty, Bushehr University of Medical Sciences, Bushehr, IR Iran
4 The Persian Gulf Tropical Medicine Research Center, Bushehr University of Medical Sciences, Bushehr, IR Iran
Article information
  • Iranian Red Crescent Medical Journal: April 01, 2016, 18 (4); e29649
  • Published Online: February 21, 2016
  • Article Type: Research Article
  • Received: May 22, 2015
  • Revised: September 24, 2015
  • Accepted: October 19, 2015
  • DOI: 10.5812/ircmj.29649

To Cite: Dezhdar S, Jahanpour F, Firouz Bakht S, Ostovar A. The Effects of Kangaroo Mother Care and Swaddling on Venipuncture Pain in Premature Neonates: A Randomized Clinical Trial, Iran Red Crescent Med J. 2016 ; 18(4):e29649. doi: 10.5812/ircmj.29649.

Copyright © 2016, Iranian Red Crescent Medical Journal. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Patients and Methods
4. Results
5. Discussion
  • 1. Fernandes A. The efficacy of kangaroo mother care, sucrose and pacifier to reduce responses of preterm infants to procedural pain. 2010;
  • 2. Memarian R. Application of nursing concepts and theories. 2011; : 134-5
  • 3. Fitzgerald M. The development of nociceptive circuits. Nat Rev Neurosci. 2005; 6(7): 507-20[DOI][PubMed]
  • 4. Cong X, Ludington-Hoe SM, McCain G, Fu P. Kangaroo Care modifies preterm infant heart rate variability in response to heel stick pain: pilot study. Early Hum Dev. 2009; 85(9): 561-7[DOI][PubMed]
  • 5. Fitzgerald M, Beggs S. The neurobiology of pain: developmental aspects. Neuroscientist. 2001; 7(3): 246-57[PubMed]
  • 6. Silveira MF, Matijasevich A, Horta BL, Bettiol H, Barbieri MA, Silva AA, et al. [Prevalence of preterm birth according to birth weight group: a systematic review]. Rev Saude Publica. 2013; 47(5): 992-1003[PubMed]
  • 7. Carbajal R, Rousset A, Danan C, Coquery S, Nolent P, Ducrocq S, et al. Epidemiology and treatment of painful procedures in neonates in intensive care units. JAMA. 2008; 300(1): 60-70[DOI][PubMed]
  • 8. Stevens B, McGrath P, Gibbins S, Beyene J, Breau L, Camfield C, et al. Procedural pain in newborns at risk for neurologic impairment. Pain. 2003; 105(1-2): 27-35[PubMed]
  • 9. Cong X, Cusson RM, Walsh S, Hussain N, Ludington-Hoe SM, Zhang D. Effects of skin-to-skin contact on autonomic pain responses in preterm infants. J Pain. 2012; 13(7): 636-45[DOI][PubMed]
  • 10. Lago P, Guadagni A, Merazzi D, Ancora G, Bellieni CV, Cavazza A, et al. Pain management in the neonatal intensive care unit: a national survey in Italy. Paediatr Anaesth. 2005; 15(11): 925-31[DOI][PubMed]
  • 11. Johnston CC, Fernandes AM, Campbell-Yeo M. Pain in neonates is different. Pain. 2011; 152(3 Suppl)-73[DOI][PubMed]
  • 12. Brummelte S, Grunau RE, Chau V, Poskitt KJ, Brant R, Vinall J, et al. Procedural pain and brain development in premature newborns. Ann Neurol. 2012; 71(3): 385-96[DOI][PubMed]
  • 13. Cheraghy SF. Assessment of pain symptoms in neonates admitted to neonatal units of hospitals in Hamedan University of Medical Sciences. J Mazandaran Univ Med Sci. 2002; 12(37): 1-2
  • 14. Saeidi R. The effect of kangaroo method on vaccination pain in infants. J Sabzevar Univ Med Sci. 2007; 4
  • 15. Carbajal R, Lenclen R, Jugie M, Paupe A, Barton BA, Anand KJ. Morphine does not provide adequate analgesia for acute procedural pain among preterm neonates. Pediatrics. 2005; 115(6): 1494-500[DOI][PubMed]
  • 16. Khoddam H, Ziaei T, Hoseini SA. The effect of skin to skin contact of mother and newborn infant pain. J Gorgan Univ Med Sci. 2002; 4(1)
  • 17. Melzack R. Pain and the neuromatrix in the brain. J Dent Educ. 2001; 65(12): 1378-82[PubMed]
  • 18. Gray L, Watt L, Blass EM. Skin-to-skin contact is analgesic in healthy newborns. Pediatrics. 2000; 105(1)[PubMed]
  • 19. Johnston CC, Stevens B, Pinelli J, Gibbins S, Filion F, Jack A, et al. Kangaroo care is effective in diminishing pain response in preterm neonates. Arch Pediatr Adolesc Med. 2003; 157(11): 1084-8[DOI][PubMed]
  • 20. Gerard CM, Harris KA, Thach BT. Spontaneous arousals in supine infants while swaddled and unswaddled during rapid eye movement and quiet sleep. Pediatrics. 2002; 110(6)[PubMed]
  • 21. van Sleuwen BE, Engelberts AC, Boere-Boonekamp MM, Kuis W, Schulpen TW, L'Hoir MP. Swaddling: a systematic review. Pediatrics. 2007; 120(4)-106[DOI][PubMed]
  • 22. van Sleuwen BE, L'Hoir MP, Engelberts AC, Westers P, Schulpen TW. Infant care practices related to cot death in Turkish and Moroccan families in the Netherlands. Arch Dis Child. 2003; 88(9): 784-8[PubMed]
  • 23. Freire NB, Garcia JB, Lamy ZC. Evaluation of analgesic effect of skin-to-skin contact compared to oral glucose in preterm neonates. Pain. 2008; 139(1): 28-33[DOI][PubMed]
  • 24. Ballantyne M, Stevens B, McAllister M, Dionne K, Jack A. Validation of the premature infant pain profile in the clinical setting. Clin J Pain. 1999; 15(4): 297-303[PubMed]
  • 25. Stevens B, Johnston C, Taddio A, Gibbins S, Yamada J. The premature infant pain profile: evaluation 13 years after development. Clin J Pain. 2010; 26(9): 813-30[DOI][PubMed]
  • 26. Reyhani T, Mohebi T, Boskabadi H, Gholami H. The effect of facilitated tucking during venipuncture on pain and physiological parameters in preterm infants. Evid Based Care. 2012; 2(2): 47-56
  • 27. Akcan E, Yigit R, Atici A. The effect of kangaroo care on pain in premature infants during invasive procedures. Turk J Pediatr. 2009; 51(1): 14-8[PubMed]
  • 28. Huang CM, Tung WS, Kuo LL, Ying-Ju C. Comparison of pain responses of premature infants to the heelstick between containment and swaddling. J Nurs Res. 2004; 12(1): 31-40[PubMed]
  • 29. Meek J, Huertas A. Cochrane review: Non-nutritive sucking, kangaroo care and swaddling/facilitated tucking are observed to reduce procedural pain in infants and young children. Evid Based Nurs. 2012; 15(3): 84-5[DOI][PubMed]
  • 30. Pillai Riddell RR, Racine NM, Turcotte K, Uman LS, Horton RE, Din Osmun L, et al. Non-pharmacological management of infant and young child procedural pain. Cochrane Database Syst Rev. 2011; (10)[DOI][PubMed]
  • 31. Johnston CC, Filion F, Campbell-Yeo M, Goulet C, Bell L, McNaughton K, et al. Kangaroo mother care diminishes pain from heel lance in very preterm neonates: a crossover trial. BMC Pediatr. 2008; 8: 13[DOI][PubMed]
  • 32. Ho S, Ho L. Effects of facilitated swaddling for controlling procedural pain in premature neonates: a randomized controlled trial. J Pain. 2012; 13(4)[DOI]
  • 33. Meyer LE, Erler T. Swaddling: a traditional care method rediscovered. World J Pediatr. 2011; 7(2): 155-60[DOI][PubMed]
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