Iranian Red Crescent Medical Journal

Published by: Kowsar

RETRACTED ARTICLE: Profile of Virulence Factors in the Multi-Drug Resistant Pseudomonas aeruginosa Strains of Human Urinary Tract Infections (UTI)

Asghar Habibi 1 and Ramin Honarmand 2 , *
Authors Information
1 Emam Reza Hospital, Birjand University of Medical Sciences, Birjand, IR Iran
2 Department of Urology, Emam Reza Hospital, Birjand University of Medical Sciences, Birjand, IR Iran
This article has been retracted. See Retraction Note.
Article information
  • Iranian Red Crescent Medical Journal: December 01, 2015, 17 (12); e26095
  • Published Online: December 22, 2015
  • Article Type: Research Article
  • Received: February 11, 2015
  • Revised: June 22, 2015
  • Accepted: November 16, 2015
  • DOI: 10.5812/ircmj.26095

To Cite: Habibi A, Honarmand R. RETRACTED ARTICLE: Profile of Virulence Factors in the Multi-Drug Resistant Pseudomonas aeruginosa Strains of Human Urinary Tract Infections (UTI), Iran Red Crescent Med J. 2015 ; 17(12):e26095. doi: 10.5812/ircmj.26095.

Copyright © 2015, Iranian Red Crescent Medical Journal. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Patients and Methods
4. Results
5. Discussion
  • 1. Mittal R, Aggarwal S, Sharma S, Chhibber S, Harjai K. Urinary tract infections caused by Pseudomonas aeruginosa: a minireview. J Infect Public Health. 2009; 2(3): 101-11[DOI][PubMed]
  • 2. Momtaz H, Karimian A, Madani M, Safarpoor Dehkordi F, Ranjbar R, Sarshar M, et al. Uropathogenic Escherichia coli in Iran: serogroup distributions, virulence factors and antimicrobial resistance properties. Ann Clin Microbiol Antimicrob. 2013; 12: 8[DOI][PubMed]
  • 3. Dormanesh B, Safarpoor Dehkordi F, Hosseini S, Momtaz H, Mirnejad R, Hoseini MJ, et al. Virulence factors and o-serogroups profiles of uropathogenic Escherichia coli isolated from Iranian pediatric patients. Iran Red Crescent Med J. 2014; 16(2)[DOI][PubMed]
  • 4. Kucheria R, Dasgupta P, Sacks SH, Khan MS, Sheerin NS. Urinary tract infections: new insights into a common problem. Postgrad Med J. 2005; 81(952): 83-6[DOI][PubMed]
  • 5. Bitsori M, Maraki S, Koukouraki S, Galanakis E. Pseudomonas aeruginosa urinary tract infection in children: risk factors and outcomes. J Urol. 2012; 187(1): 260-4[DOI][PubMed]
  • 6. Ra'oof WM. Distribution of algD, lasB, pilB and nan1 genes among MDR clinical isolates of Pseudomonas aeruginosa in respect to site of infection. Tikrit Med J. 2011; 17(2): 148-60
  • 7. Rashno Taee S, Khansarinejad B, Abtahi H, Najafimosleh M, Ghaznavi-Rad E. Detection of algD, oprL and exoA Genes by New Specific Primers as an Efficient, Rapid and Accurate Procedure for Direct Diagnosis of Pseudomonas aeruginosa Strains in Clinical Samples. Jundishapur J Microbiol. 2014; 7(10)[DOI][PubMed]
  • 8. Lister PD, Wolter DJ, Hanson ND. Antibacterial-resistant Pseudomonas aeruginosa: clinical impact and complex regulation of chromosomally encoded resistance mechanisms. Clin Microbiol Rev. 2009; 22(4): 582-610[DOI][PubMed]
  • 9. MacKenzie JR, Fowler K, Hollman AS, Tappin D, Murphy AV, Beattie TJ, et al. The value of ultrasound in the child with an acute urinary tract infection. Br J Urol. 1994; 74(2): 240-4[PubMed]
  • 10. Urinary Tract Infection in Children: Diagnosis, Treatment and Long-term Management. 2007; [PubMed]
  • 11. Performance standards for antimicrobial susceptibility testing; twenty-second informational supplement. 2012; 32(3)
  • 12. Sambrook J, Russell David W. Molecular cloning: A laboratory manual. 1989; : 2100
  • 13. Strateva T. [Ph.D. Dissertation.]. Sofia, Bulgaria: Medical University of Sofia, Bulgaria; 2008;
  • 14. Lanotte P, Watt S, Mereghetti L, Dartiguelongue N, Rastegar-Lari A, Goudeau A, et al. Genetic features of Pseudomonas aeruginosa isolates from cystic fibrosis patients compared with those of isolates from other origins. J Med Microbiol. 2004; 53: 73-81[DOI][PubMed]
  • 15. Nickavar A, Sotoudeh K. Treatment and prophylaxis in pediatric urinary tract infection. Int J Prev Med. 2011; 2(1): 4-9[PubMed]
  • 16. Kumar Maji S, Maity C, Kumar Halder S, Paul T, Kumar Kundu P, Chandra Mondal K. Studies on drug sensitivity and bacterial prevalence of UTI in tribal population of paschim medinipur, West Bengal, India. Jundishapur J Microbiol. 2012; 6(1): 42-6[DOI]
  • 17. Zorc JJ, Kiddoo DA, Shaw KN. Diagnosis and management of pediatric urinary tract infections. Clin Microbiol Rev. 2005; 18(2): 417-22[DOI][PubMed]
  • 18. Haghi-Ashteiani M, Sadeghifard N, Abedini M, Taheri-Kalani S, Soroush M. Etiology and antibacterial resistance of bacterial urinary tract infections in Children’s Medical Center, Tehran, Iran. Acta Med Iran. 2007; 45(2): 153-7
  • 19. Mirsoleymani SR, Salimi M, Shareghi Brojeni M, Ranjbar M, Mehtarpoor M. Bacterial pathogens and antimicrobial resistance patterns in pediatric urinary tract infections: A four-year surveillance study (2009–2012). Int J Pediatr. 2014; : 1-6
  • 20. Nandi A, Bhattacharya S, Biswas S, Chattopadhyay S. A study on Metallo-β lactamase producing Imepenem nonsusceptible multi-drug resistant Pseudomonas aeruginosa in different clinical specimens in a tertiary care hospital in Kolkata. IOSR J Dent Med Sci. 2014; 13(6): 13-7[DOI]
  • 21. Abaeze S, Abasiama JS. The prevalence of urinary catheter related infections in federal medical centre Abeokuta Nigeria. Int J Pharm Biomed Sci . 2011; 2(3): 81-5
  • 22. Takeyama K, Kunishima Y, Matsukawa M, Takahashi S, Hirose T, Kobayashi N, et al. Multidrug-resistant Pseudomonas aeruginosa isolated from the urine of patients with urinary tract infection. J Infect Chemother. 2002; 8(1): 59-63[DOI][PubMed]
  • 23. Jombo GT, Jonah P, Ayeni JA. Multiple resistant Pseudomonas aeruginosa in contemporary medical practice: findings from urinary isolates at a Nigerian University Teaching Hospital. Niger J Physiol Sci. 2008; 23(1-2): 105-9[PubMed]
  • 24. Chikwendu CI, Amadi ES, Obi RK. Prevalence and antimicrobial resistance in Pseudomonas aeruginosa and Klebsiella pneumonia isolates from non-clinical urine samples. NY Sci J. 2010; 3(11): 194-200
  • 25. Gencer S, Ak O, Benzonana N, Batirel A, Ozer S. Susceptibility patterns and cross resistances of antibiotics against Pseudomonas aeruginosa in a teaching hospital of Turkey. Ann Clin Microbiol Antimicrob. 2002; 1: 2[PubMed]
  • 26. Khajuria A, Praharaj AK, Kumar M, Grover N. Emergence of NDM - 1 in the Clinical Isolates of Pseudomonas aeruginosa in India. J Clin Diagn Res. 2013; 7(7): 1328-31[DOI][PubMed]
  • 27. Moehario LH, Hartono TS, Wardoyo EH, Tjoa E. Trend of antibiotics susceptibility of multidrugs resistance Pseudomonas aeruginosa in Jakarta and surrounding areas from 2004 to 2010. Afr J Microbiol Res. 2012; 6(9): 2222-9
  • 28. Onguru P, Erbay A, Bodur H, Baran G, Akinci E, Balaban N, et al. Imipenem-resistant Pseudomonas aeruginosa: risk factors for nosocomial infections. J Korean Med Sci. 2008; 23(6): 982-7[DOI][PubMed]
  • 29. Neuner EA, Sekeres J, Hall GS, van Duin D. Experience with fosfomycin for treatment of urinary tract infections due to multidrug-resistant organisms. Antimicrob Agents Chemother. 2012; 56(11): 5744-8[DOI][PubMed]
  • 30. Tsutsui A, Suzuki S, Yamane K, Matsui M, Konda T, Marui E, et al. Genotypes and infection sites in an outbreak of multidrug-resistant Pseudomonas aeruginosa. J Hosp Infect. 2011; 78(4): 317-22[DOI][PubMed]
  • 31. Shigemura K, Takase R, Osawa K, Takaba K, Nomi M, Fujisawa M, et al. Emergence and prevention measures for multidrug resistant Pseudomonas aeruginosa in catheter-associated urinary tract infection in spinal cord injury patients. Spinal Cord. 2015; 53(1): 70-4[DOI][PubMed]
  • 32. Fazeli N, Momtaz H. Virulence Gene Profiles of Multidrug-Resistant Pseudomonas aeruginosa Isolated From Iranian Hospital Infections. Iran Red Crescent Med J. 2014; 16(10)[DOI][PubMed]
  • 33. Hamood AN, Griswold JA, Duhan CM. Production of extracellular virulence factors by Pseudomonas aeruginosa isolates obtained from tracheal, urinary tract, and wound infections. J Surg Res. 1996; 61(2): 425-32[DOI][PubMed]
  • 34. Nikbin VS, Aslani MM, Sharafi Z, Hashemipour M, Shahcheraghi F, Ebrahimipour GH. Molecular identification and detection of virulence genes among Pseudomonas aeruginosa isolated from different infectious origins. Iran J Microbiol. 2012; 4(3): 118-23[PubMed]
  • 35. Bradbury RS, Roddam LF, Merritt A, Reid DW, Champion AC. Virulence gene distribution in clinical, nosocomial and environmental isolates of Pseudomonas aeruginosa. J Med Microbiol. 2010; 59: 881-90[DOI][PubMed]
  • 36. Mitov I, Strateva T, Markova B. Prevalence of virulence genes among bulgarian nosocomial and cystic fibrosis isolates of pseudomonas aeruginosa. Braz J Microbiol. 2010; 41(3): 588-95[DOI][PubMed]
  • 37. Shaver CM, Hauser AR. Relative contributions of Pseudomonas aeruginosa ExoU, ExoS, and ExoT to virulence in the lung. Infect Immun. 2004; 72(12): 6969-77[DOI][PubMed]
  • 38. Pankhaniya RR, Tamura M, Allmond LR, Moriyama K, Ajayi T, Wiener-Kronish JP, et al. Pseudomonas aeruginosa causes acute lung injury via the catalytic activity of the patatin-like phospholipase domain of ExoU. Crit Care Med. 2004; 32(11): 2293-9[PubMed]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .
Readers' Comments