Iranian Red Crescent Medical Journal

Published by: Kowsar

Intravitreal Clindamycin in the Treatment of Unresponsive Zone One Toxoplasmic Chorioretinitis: A Case Report

Seyedeh Maryam Hosseini 1 , Mojtaba Abrishami 1 , 2 , * and Mehran Mehdi Zadeh 1
Authors Information
1 Retina Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, IR Iran
2 Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, IR Iran
Article information
  • Iranian Red Crescent Medical Journal: November 30, 2014, 16 (11); e15428
  • Published Online: November 17, 2014
  • Article Type: Case Report
  • Received: October 15, 2013
  • Revised: August 30, 2014
  • Accepted: September 2, 2014
  • DOI: 10.5812/ircmj.15428

To Cite: Hosseini S M, Abrishami M, Mehdi Zadeh M. Intravitreal Clindamycin in the Treatment of Unresponsive Zone One Toxoplasmic Chorioretinitis: A Case Report, Iran Red Crescent Med J. 2014 ; 16(11):e15428. doi: 10.5812/ircmj.15428.

Copyright © 2014, Iranian Red Crescent Medical Journal. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Introduction
2. Case Presentation
3. Discussion
  • 1. Dodds EM. Ocular toxoplasmosis: clinical presentations, diagnosis and therapy. Focal Points: Clinical Modules for Ophthalmologists. 1999;
  • 2. Holland GN, Lewis KG. An update on current practices in the management of ocular toxoplasmosis. Am J Ophthalmol. 2002; 134(1): 102-14[PubMed]
  • 3. Rothova A, Meenken C, Buitenhuis HJ, Brinkman CJ, Baarsma GS, Boen-Tan TN, et al. Therapy for Ocular Toxoplasmosis. Am J Ophthalmol. 1993; 115(4): 517-23[DOI]
  • 4. Engstrom RE, Holland GN, Nussenblatt RB, Jabs DA. Current Practices in the Management of Ocular Toxoplasmosis. Am J Ophthalmol. 1991; 111(5): 601-10[DOI]
  • 5. Opremcak E, Scales DK, Sharpe MR. Trimethoprim-Sulfamethoxazole Therapy for Ocular Toxoplasmosis. Ophthalmology. 1992; 99(6): 920-5[DOI]
  • 6. Soheilian M, Sadoughi MM, Ghajarnia M, Dehghan MH, Yazdani S, Behboudi H, et al. Prospective randomized trial of trimethoprim/sulfamethoxazole versus pyrimethamine and sulfadiazine in the treatment of ocular toxoplasmosis. Ophthalmology. 2005; 112(11): 1876-82[DOI][PubMed]
  • 7. Bonfioli AA, Orefice F. Toxoplasmosis. Semin Ophthalmol. 2005; 20(3): 129-41[DOI][PubMed]
  • 8. Kishore K, Conway MD, Peyman GA. Intravitreal clindamycin and dexamethasone for toxoplasmic retinochoroiditis. Ophthalmic Surg Lasers. 2001; 32(3): 183-92[PubMed]
  • 9. Sobrin L, Kump LI, Foster CS. Intravitreal clindamycin for toxoplasmic retinochoroiditis. Retina. 2007; 27(7): 952-7[DOI][PubMed]
  • 10. Wong R, dell'Omo R, Marino M, Hussein B, Okhravi N, Pavesio CE. Toxoplasma gondii: an atypical presentation of toxoplasma as optic disc swelling and hemispherical retinal vein occlusion treated with intravitreal clindamycin. Int Ophthalmol. 2009; 29(3): 195-8[DOI][PubMed]
  • 11. Lasave AF, Diaz-Llopis M, Muccioli C, Belfort RJ, Arevalo JF. Intravitreal clindamycin and dexamethasone for zone 1 toxoplasmic retinochoroiditis at twenty-four months. Ophthalmology. 2010; 117(9): 1831-8[DOI][PubMed]
  • 12. Martinez CE, Zhang D, Conway MD, Peyman GA. Successful management of ocular toxoplasmosis during pregnancy using combined intraocular clindamycin and dexamethasone with systemic sulfadiazine. Int Ophthalmol. 1998; 22(2): 85-8[PubMed]
  • 13. Nicholson DH, Wolchok EB. Ocular Toxoplasmosis in an Adult Receiving Long-Term Corticosteroid Therapy. Archives of Ophthalmology. 1976; 94(2): 248-54[DOI]
  • 14. Nozik RA. Results of treatment of ocular toxoplasmosis with injectable corticosteroids. Trans Sect Ophthalmol Am Acad Ophthalmol Otolaryngol. 1977; 83(5): 811-8[PubMed]
  • 15. O'Connor GR, Frenkel JK. Editorial: Dangers of steroid treatment in toxoplasmosis. Periocular injections and systemic therapy. Arch Ophthalmol. 1976; 94(2): 213[PubMed]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:



Create Citiation Alert
via Google Reader

Readers' Comments