Diagnostic Efficacy of Lsa63 Antigen for Human Leptospirosis

Authors Information
Article Notes and Dates
To Cite : Alizadeh S A, Eshraghi S S, Pourmand M R, Naserpour T, Abdollahpour G, et al. Diagnostic Efficacy of Lsa63 Antigen for Human Leptospirosis, Iran Red Crescent Med J. 2014 ;16(3):e14753. doi: 10.5812/ircmj.14753.
Abstract
1. Background
2. Objectives
3. Material and Methods
4. Results
5. Discussion
Acknowledgements
Footnotes
References
  • 1. Chalayon P, Chanket P, Boonchawalit T, Chattanadee S, Srimanote P, Kalambaheti T. Leptospirosis serodiagnosis by ELISA based on recombinant outer membrane protein. Trans R Soc Trop Med Hyg. 2011; 105(5): 289-97[DOI][PubMed]
  • 2. Bajani MD, Ashford DA, Bragg SL, Woods CW, Aye T, Spiegel RA, et al. Evaluation of four commercially available rapid serologic tests for diagnosis of leptospirosis. J Clin Microbiol. 2003; 41(2): 803-9[PubMed]
  • 3. Ahmed A, Engelberts MF, Boer KR, Ahmed N, Hartskeerl RA. Development and validation of a real-time PCR for detection of pathogenic leptospira species in clinical materials. PLoS One. 2009; 4(9)[DOI][PubMed]
  • 4. Sun A, Wang Y, Du P, Wu S, Yan J. A sensitive and specific IgM-ELISA for the serological diagnosis of human leptospirosis using a rLipL32/1-LipL21-OmpL1/2 fusion protein. Biomed Environ Sci. 2011; 24(3): 291-9[DOI][PubMed]
  • 5. Oliveira TR, Longhi MT, de Morais ZM, Romero EC, Blanco RM, Kirchgatter K, et al. Evaluation of leptospiral recombinant antigens MPL17 and MPL21 for serological diagnosis of leptospirosis by enzyme-linked immunosorbent assays. Clin Vaccine Immunol. 2008; 15(11): 1715-22[DOI][PubMed]
  • 6. Dey S, Mohan CM, Ramadass P, Nachimuthu K. Diagnosis of leptospirosis by recombinant antigen based single serum dilution ELISA. Indian J Med Res. 2008; 128(2): 172-7[PubMed]
  • 7. Swapna RN, Tuteja U, Nair L, Sudarsana J. Seroprevalence of leptospirosis in high risk groups in Calicut, North Kerala, India. Indian J Med Microbiol. 2006; 24(4): 349-52[PubMed]
  • 8. Perwez K, Suman VB, Kumar NA, Hussain MA. Leptospirosis in Febrile Patients: Diagnosis by serology and polymerase chain reaction. J Biol Life Sci. 2011; 2(1): 1-10
  • 9. Adler B, de la Pena Moctezuma A. Leptospira and leptospirosis. Vet Microbiol. 2010; 140(3-4): 287-96[DOI][PubMed]
  • 10. Ooteman MC, Vago AR, Koury MC. Evaluation of MAT, IgM ELISA and PCR methods for the diagnosis of human leptospirosis. J Microbiol Methods. 2006; 65(2): 247-57[DOI][PubMed]
  • 11. Bharti AR, Nally JE, Ricaldi JN, Matthias MA, Diaz MM, Lovett MA, et al. Leptospirosis: a zoonotic disease of global importance. Lancet Infect Dis. 2003; 3(12): 757-71
  • 12. Joseph S, Thomas N, Thangapandian E, Singh VP, Verma R, Srivastava SK. Evaluation and comparison of native and recombinant LipL21 protein-based ELISAs for diagnosis of bovine leptospirosis. J Vet Sci. 2012; 13(1): 99-101[PubMed]
  • 13. Vieira ML, de Morais ZM, Goncales AP, Romero EC, Vasconcellos SA, Nascimento AL. Lsa63, a newly identified surface protein of Leptospira interrogans binds laminin and collagen IV. J Infect. 2010; 60(1): 52-64[DOI][PubMed]
  • 14. WHO . Human Leptospirosis: Guidance for Diagnosis, Surveilance and Control. 2003;
  • 15. Srimanote P, Wongdeethai N, Jieanampunkul P, Samonkiert S, Leepiyasakulchai C, Kalambaheti T, et al. Recombinant ligA for leptospirosis diagnosis and ligA among the Leptospira spp. clinical isolates. J Microbiol Methods. 2008; 72(1): 73-81[DOI][PubMed]
  • 16. Palaniappan RU, Chang YF, Hassan F, McDonough SP, Pough M, Barr SC, et al. Expression of leptospiral immunoglobulin-like protein by Leptospira interrogans and evaluation of its diagnostic potential in a kinetic ELISA. J Med Microbiol. 2004; 53: 975-84[PubMed]
  • 17. Vasconcellos FA, Coutinho ML, da Silva EF, Fernandes CP, Monte LG, Seyffert N, et al. Testing different antigen capture ELISA formats for detection of Leptospira spp. in human blood serum. Trans R Soc Trop Med Hyg. 2010; 104(4): 259-64[DOI][PubMed]
  • 18. Hull-Jackson C, Glass MB, Ari MD, Bragg SL, Branch SL, Whittington CU, et al. Evaluation of a commercial latex agglutination assay for serological diagnosis of leptospirosis. J Clin Microbiol. 2006; 44(5): 1853-5
  • 19. Sakhaee E, Abdollah pour GR. Detection of leptospiral antibodies by microscopic agglutination test in north–east of Iran. Asian Pac J Cancer Prev. 2011; 1(3): 227-9[DOI]
  • 20. Hartskeerl RA, Goris M, Smits HL. Manual of laboratory methods for the diagnosis of leptospirosis. 2004;
  • 21. Sambrook J, Fritsch EF, Maniatis T. Molecular cloning. 1989;
  • 22. Senthilkumar TMA, Subathra M, Phil M, Ramadass P, Ramaswamy V. Rapid serodiagnosis of leptospirosis by latex agglutination test and flow-through assay. Indian J Med Microbiol. 2008; 26(1): 45
  • 23. Dey S, Mohan CM, Kumar TMAS, Ramadass P, Nainar AM, Nachimuthu K. Recombinant LipL32 antigen-based single serum dilution ELISA for detection of canine leptospirosis. Vet Microbiol. 2004; 103(1–2): 99-106[DOI]
  • 24. Schisterman EF, Perkins NJ, Liu A, Bondell H. Optimal cut-point and its corresponding Youden Index to discriminate individuals using pooled blood samples. Epidemiol. 2005; 16(1): 73-81[DOI]
  • 25. Flannery B, Costa D, Carvalho FP, Guerreiro H, Matsunaga J, Da Silva ED, et al. Evaluation of recombinant Leptospira antigen-based enzyme-linked immunosorbent assays for the serodiagnosis of leptospirosis. J Clin Microbiol. 2001; 39(9): 3303-10[DOI]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:

Author(s):

Article(s):

Create Citiaion Alert via Google Reader

Cited By:

Iranian Red Crescent Medical Journal accepts terms & conditions of:

International Committee of Medical Journal Editors (ICMJE) Citedby Linking DOI enabled Crossref iThenticate COPE Cross Check