Improvement in Biochemical Parameters in Patients with Type 2 Diabetes After Twenty-Four Sessions of Aerobic Exercise: A Randomized Controlled Trial

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To Cite : Rahbar S, Naimi S S, Soltani A R, Rahimi A, Akbarzadeh Baghban A, et al. Improvement in Biochemical Parameters in Patients with Type 2 Diabetes After Twenty-Four Sessions of Aerobic Exercise: A Randomized Controlled Trial, Iran Red Crescent Med J. 2017 ;19(7):e13931. doi: 10.5812/ircmj.13931.
Abstract
1. Background
2. Methods
3. Results
4. Discussion
Acknowledgements
Footnotes
References
  • 1. Byrkjeland R, Njerve IU, Anderssen S, Arnesen H, Seljeflot I, Solheim S. Effects of exercise training on HbA1c and VO2peak in patients with type 2 diabetes and coronary artery disease: A randomised clinical trial. Diab Vasc Dis Res. 2015; 12(5): 325-33[DOI][PubMed]
  • 2. Shah SM, Ali R, Loney T, Aziz F, ElBarazi I, Al Dhaheri S, et al. Prevalence of Diabetes among Migrant Women and Duration of Residence in the United Arab Emirates: A Cross Sectional Study. PLoS One. 2017; 12(1)[DOI][PubMed]
  • 3. Jayan A, Dubey RK, Padmavati P, Jha AC, Gautam N. Association of Lipid Profile with fasting and Post Prandial Glucose Level in type 2 Diabetic Patients. J Univ College Med Sci. 2015; 3(1): 2[DOI]
  • 4. Farzadfar F, Finucane MM, Danaei G, Pelizzari PM, Cowan MJ, Paciorek CJ, et al. National, regional, and global trends in serum total cholesterol since 1980: systematic analysis of health examination surveys and epidemiological studies with 321 country-years and 3· 0 million participants. Lancet. 2011; 377(9765): 578-86
  • 5. Jenkins AJ, Joglekar MV, Hardikar AA, Keech AC, O'Neal DN, Januszewski AS. Biomarkers in Diabetic Retinopathy. Rev Diabet Stud. 2015; 12(1-2): 159-95[DOI][PubMed]
  • 6. Forouhi NG, Wareham NJ. Epidemiology of diabetes. Medicine (Abingdon). 2014; 42(12): 698-702[DOI][PubMed]
  • 7. Elder DH, Singh JS, Levin D, Donnelly LA, Choy AM, George J, et al. Mean HbA1c and mortality in diabetic individuals with heart failure: a population cohort study. Eur J Heart Fail. 2016; 18(1): 94-102[DOI][PubMed]
  • 8. Khan HA, Sobki SH, Khan SA. Association between glycaemic control and serum lipids profile in type 2 diabetic patients: HbA1c predicts dyslipidaemia. Clin Exp Med. 2007; 7(1): 24-9[DOI][PubMed]
  • 9. Hu FB, Meigs JB, Li TY, Rifai N, Manson JE. Inflammatory markers and risk of developing type 2 diabetes in women. Diabetes. 2004; 53(3): 693-700[PubMed]
  • 10. Klausen K, Borch-Johnsen K, Feldt-Rasmussen B, Jensen G, Clausen P, Scharling H, et al. Very low levels of microalbuminuria are associated with increased risk of coronary heart disease and death independently of renal function, hypertension, and diabetes. Circulation. 2004; 110(1): 32-5[DOI][PubMed]
  • 11. Stehouwer CD, Smulders YM. Microalbuminuria and risk for cardiovascular disease: Analysis of potential mechanisms. J Am Soc Nephrol. 2006; 17(8): 2106-11[DOI][PubMed]
  • 12. Zanuso S, Jimenez A, Pugliese G, Corigliano G, Balducci S. Exercise for the management of type 2 diabetes: a review of the evidence. Acta Diabetol. 2010; 47(1): 15-22[DOI][PubMed]
  • 13. Mavros Y, Kay S, Anderberg KA, Baker MK, Wang Y, Zhao R, et al. Changes in insulin resistance and HbA1c are related to exercise-mediated changes in body composition in older adults with type 2 diabetes: interim outcomes from the GREAT2DO trial. Diabetes Care. 2013; 36(8): 2372-9[DOI][PubMed]
  • 14. Byrkjeland R, Njerve IU, Arnesen H, Seljeflot I, Solheim S. Reduced endothelial activation after exercise is associated with improved HbA1c in patients with type 2 diabetes and coronary artery disease. Diabetes Vasc Dis Res. 2017; 14(2): 94-103
  • 15. Standards of Medical Care in Diabetes-2017: Summary of Revisions. Diabetes Care. 2017; 40-5[DOI][PubMed]
  • 16. Maiorana AJ, Naylor LH, Exterkate A, Swart A, Thijssen DH, Lam K, et al. The impact of exercise training on conduit artery wall thickness and remodeling in chronic heart failure patients. Hypertension. 2011; 57(1): 56-62[DOI][PubMed]
  • 17. Pena YT, Gordon L, Morrison E, McGrowder D, Garwood D. changes in clinical and metabolic parameters in patients with type 2 diabetes mellitus after exercise therapy. Can J Diabetes. 2009; 33(3): 273-4
  • 18. Tessier D, Menard J, Fulop T, Ardilouze JL, Roy MA, Dubuc N, et al. Effects of aerobic physical exercise in the elderly with type 2 diabetes mellitus. Arch Gerontol Geriatrics. 2000; 31(2): 121-32
  • 19. Okada S, Hiuge A, Makino H, Nagumo A, Takaki H, Konishi H, et al. Effect of exercise intervention on endothelial function and incidence of cardiovascular disease in patients with type 2 diabetes. J Atheroscler Thromb. 2010; 17(8): 828-33[PubMed]
  • 20. American Diabetes A. Standards of Medical Care in Diabetes-2016 Abridged for Primary Care Providers. Clin Diabetes. 2016; 34(1): 3-21[DOI][PubMed]
  • 21. Fakhry F, Spronk S, de Ridder M, den Hoed PT, Hunink MG. Long-term effects of structured home-based exercise program on functional capacity and quality of life in patients with intermittent claudication. Arch Phys Med Rehabil. 2011; 92(7): 1066-73[DOI][PubMed]
  • 22. Cohen ND, Dunstan DW, Robinson C, Vulikh E, Zimmet PZ, Shaw JE. Improved endothelial function following a 14-month resistance exercise training program in adults with type 2 diabetes. Diabetes Res Clin Pract. 2008; 79(3): 405-11[DOI][PubMed]
  • 23. Church TS, Blair SN, Cocreham S, Johannsen N, Johnson W, Kramer K, et al. Effects of aerobic and resistance training on hemoglobin A1c levels in patients with type 2 diabetes: a randomized controlled trial. JAMA. 2010; 304(20): 2253-62[DOI][PubMed]
  • 24. Aggarwala J, Sharma S, Saroochi AJ, Sarkar A. Effects of aerobic exercise on blood glucose levels and lipid profile in Diabetes Mellitus type 2 subjects. A l Ameen J Med Sci . 2016; 9(1): 65-9
  • 25. Pattyn N, Cornelissen VA, Eshghi SR, Vanhees L. The effect of exercise on the cardiovascular risk factors constituting the metabolic syndrome: a meta-analysis of controlled trials. Sports Med. 2013; 43(2): 121-33[DOI][PubMed]
  • 26. Schuit AJ, Schouten EG, Miles TP, Evans WJ, Saris WH, Kok FJ. The effect of six months training on weight, body fatness and serum lipids in apparently healthy elderly Dutch men and women. Int J Obes Relat Metab Disord. 1998; 22(9): 847-53[PubMed]
  • 27. Fritz T, Wandell P, Aberg H, Engfeldt P. Walking for exercise--does three times per week influence risk factors in type 2 diabetes? Diabetes Res Clin Pract. 2006; 71(1): 21-7[DOI][PubMed]
  • 28. Barter PJ. High density lipoprotein: a therapeutic target in type 2 diabetes. Endocrinol Metab (Seoul). 2013; 28(3): 169-77[DOI][PubMed]
  • 29. Iborra RT, Ribeiro IC, Neves MQ, Charf AM, Lottenberg SA, Negrao CE, et al. Aerobic exercise training improves the role of high-density lipoprotein antioxidant and reduces plasma lipid peroxidation in type 2 diabetes mellitus. Scand J Med Sci Sports. 2008; 18(6): 742-50[DOI][PubMed]
  • 30. Toth PP. High-density lipoprotein and cardiovascular risk. Circulation. 2004; 109(15): 1809-12[DOI][PubMed]
  • 31. Couillard C, Despres JP, Lamarche B, Bergeron J, Gagnon J, Leon AS, et al. Effects of endurance exercise training on plasma HDL cholesterol levels depend on levels of triglycerides: evidence from men of the Health, Risk Factors, Exercise Training and Genetics (HERITAGE) Family Study. Arterioscler Thromb Vasc Biol. 2001; 21(7): 1226-32[PubMed]
  • 32. Fonong T, Toth MJ, Ades PA, Katzel LI, Calles-Escandon J, Poehlman ET. Relationship between physical activity and HDL-cholesterol in healthy older men and women: a cross-sectional and exercise intervention study. Atherosclerosis. 1996; 127(2): 177-83[PubMed]
  • 33. Fahlman MM, Boardley D, Lambert CP, Flynn MG. Effects of endurance training and resistance training on plasma lipoprotein profiles in elderly women. J Gerontol A Biol Sci Med Sci. 2002; 57(2)-60[PubMed]
  • 34. Mawi M. Effect of aerobic exercise on blood lipid levels in postmenopausal women. Universa Medicina. 2016; 28(1): 17-24
  • 35. Hatunic M, Finucane F, Burns N, Gasparro D, Nolan JJ. Vascular inflammatory markers in early-onset obese and type 2 diabetes subjects before and after three months' aerobic exercise training. Diab Vasc Dis Res. 2007; 4(3): 231-4[DOI][PubMed]
  • 36. Kadoglou NP, Iliadis F, Angelopoulou N, Perrea D, Ampatzidis G, Liapis CD, et al. The anti-inflammatory effects of exercise training in patients with type 2 diabetes mellitus. Eur J Cardiovasc Prev Rehabil. 2007; 14(6): 837-43[DOI][PubMed]
  • 37. Kondo T, Kobayashi I, Murakami M. Effect of exercise on circulating adipokine levels in obese young women. Endocr J. 2006; 53(2): 189-95[PubMed]
  • 38. Balducci S, Zanuso S, Nicolucci A, Fernando F, Cavallo S, Cardelli P, et al. Anti-inflammatory effect of exercise training in subjects with type 2 diabetes and the metabolic syndrome is dependent on exercise modalities and independent of weight loss. Nutr Metab Cardiovasc Dis. 2010; 20(8): 608-17[DOI][PubMed]
  • 39. Saeed F, Naga Pavan Kumar Devaki P, Mahendrakar L, Holley JL. Exercise-induced proteinuria? J Fam Pract. 2012; 61(1): 23-6[PubMed]
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