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Difference in Relative Telomere Length Between Sudanese and Chinese Individuals

Document Type : Research articles

Authors

1 1- Department of Microbiology and Immunology, College of Medical Laboratory, Dalian Medical University, Dalian 116044, China. 2- Department of Parasitology and Medical Entomology, Faculty of Medical Laboratory Sciences, University of El Imam El Mahdi, Kosti, Sudan.

2 Department of Microbiology and Immunology, College of Medical Laboratory, Dalian Medical University, Dalian 116044, China.

Abstract

Background: Racial/ethnic variations in the relative telomere length have been clearly described or infrequently studied. The relative telomere length has emerged as a biological aging marker; however, the difference in the telomere length between Sudanese and Chinese individuals is unclear.
Objectives: The present study examined the difference in the relative telomere length between Sudanese and Chinese individuals.
Methods: The blood samples of Sudanese and Chinese healthy individuals were randomly collected, and their deoxyribonucleic acid was obtained in this study. The relative telomere length was measured by quantitative polymerase chain reaction. The difference in the relative telomere length was analyzed using the Mann-Whitney U test. The degree of distribution in the relative telomere length was assessed using a two-sample Kolmogorov-Smirnov Z test.
Results: According to the obtained results, the difference in the relative telomere length between Sudanese and Chinese individuals was statistically significant (P<0.05). The frequency of the relative telomere length distributed in Chinese individuals was statistically higher than that reported for the Sudanese subjects (P<0.05).
Conclusions: A great difference was observed in the relative telomere length between Sudanese and Chinese populations indicating the difference between Sudanese and Chinese races.

Keywords

References
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Iranian Red Crescent Medical Journal (IRCMJ)
Volume 22, Issue 9 - Serial Number 9
2020
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History
  • Receive Date: 31 August 2020
  • Revise Date: 30 May 2024
  • Accept Date: 27 January 2024
  • First Publish Date: 27 January 2024
  • Publish Date: 01 September 2020
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